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Russian Chemical Bulletin

, Volume 58, Issue 7, pp 1533–1537 | Cite as

Alkyl 2-alkoxy(aryloxy)-2-isocyanato-3,3,3-trifluoropropionates

  • V. B. Sokolov
  • T. V. Goreva
  • T. A. Epishina
  • A. Yu. Aksinenko
Brief Communications

Abstract

Previously unknown fluorinated α-alkoxy(aryloxy)alkylisocyanates, the esters of α-alkoxy and α-aryloxy-2-isocyanato-3,3,3-trifluoropropionic acids, were obtained. The synthetic potential of these compounds were demonstrated in reactions with anilines leading to 2-substituted 3,3,3-trifluoroalanine derivatives.

Key words

methyl trifluoropyruvate alkoxycarbonylimines carbamates isocyanates amino acids aminals alcohols anilines ureas phosphorus pentachloride fluoroorganic compounds 

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Copyright information

© Springer Science+Business Media, Inc.  2009

Authors and Affiliations

  • V. B. Sokolov
    • 1
  • T. V. Goreva
    • 1
  • T. A. Epishina
    • 1
  • A. Yu. Aksinenko
    • 1
  1. 1.Institute of Physiologically Active SubstancesRussian Academy of SciencesMoscow RegionRussian Federation

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