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Three-component condensation of 5-aminopyrazole derivatives with isatins and Meldrum’s acid. Synthesis of 1,7-dihydrospiro[pyrazolo[3,4-b]-pyridine-4,3′-indole]-2′,6(1′H,5H)-diones

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Abstract

A new method for the synthesis of hitherto unknown substituted 1,7-dihydrospiro-[pyrazolo[3,4-b]pyridine-4,3′-indole]-2′,6(1′H,5H)-diones based on three-component condensation of 5-aminopyrazoles with Meldrum’s acid and isatins is developed.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    B. V. Lichitsky, A. N. Komogortsev, A. A. Dudinov & M. M. Krayushkin

Authors
  1. B. V. Lichitsky
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  2. A. N. Komogortsev
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  3. A. A. Dudinov
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  4. M. M. Krayushkin
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Correspondence to M. M. Krayushkin.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1460–1464, July, 2009.

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Lichitsky, B.V., Komogortsev, A.N., Dudinov, A.A. et al. Three-component condensation of 5-aminopyrazole derivatives with isatins and Meldrum’s acid. Synthesis of 1,7-dihydrospiro[pyrazolo[3,4-b]-pyridine-4,3′-indole]-2′,6(1′H,5H)-diones. Russ Chem Bull 58, 1504–1508 (2009). https://doi.org/10.1007/s11172-009-0202-4

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  • DOI: https://doi.org/10.1007/s11172-009-0202-4

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