Russian Chemical Bulletin

, Volume 57, Issue 2, pp 431–433 | Cite as

Reactions of the paramagnetic quaternary Mannich base in an alkaline medium

Brief Communications


The catalytic action of aqueous NaOH at 20 °C on 2,2,6,6-tetramethyl-3-(N-methyl-piperidiniomethyl)-4-oxopiperidine 1-oxyl iodide rapidly resulted in the formation (k = 57 L mol−1 s−1) of a paramagnetic ketone with an activated double bond: 2,2,6,6-tetramethyl-3-methylidene-4-oxopiperidine 1-oxyl. The latter underwent slow transformation into a nitroxyl biradical containing an activated double bond and a methylene bridge linking positions 3 and 3′.

Key words

paramagnetic Mannich base kinetics rate constants reaction mechanism nitroxyl radicals 


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Copyright information

© Springer Science+Business Media, Inc.  2008

Authors and Affiliations

  1. 1.N. M. Emanuel Institute of Biochemical PhysicsRussian Academy of SciencesMoscowRussian Federation

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