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Russian Chemical Bulletin

, Volume 56, Issue 4, pp 606–620 | Cite as

Enzymatic methods of analysis: Novel approaches and applications

  • T. N. Shekhovtsova
  • S. V. Muginova
  • I. A. Veselova
Article

Abstract

The results of a series of investigations dealing with the development of enzymatic methods for determination of biologically active compounds, viz., inhibitors, activators, and substrates of native and immobilized enzymes of the oxidoreductase (peroxidases, alcohol dehydrogenases) and hydrolase (alkaline and acid phosphatases) classes isolated from diverse sources are summarized. Novel original approaches, proposed by the authors, for improving the sensitivity, selectivity, and rapidity of the methods are discussed. Numerous examples of application of the developed enzymatic procedures for the analysis of a wide range of samples are given.

Key words

enzymatic methods of analysis inhibitors activators substrates immobilized enzymes test methods environmental samples biological fluids pharmaceuticals foodstuffs 

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References

  1. 1.
    T. N. Shekhovtsova, Sorosovskii obrazovatel’nyi zhurnal [Soros Educational Journal], 2000, 6, 44.Google Scholar
  2. 2.
    T. N. Shekhovtsova, S. V. Muginova, and I. A. Veselova, Ross. Khim. Zhurn., 2004, 48, 73 [Mendeleev Chem. J., 2004, 48 (Engl. Transl.)].Google Scholar
  3. 3.
    E. B. Nikol’skaya, G. A. Evtyugin, and T. N. Shekhovtsova, Zhurn. Analit. Khim., 1994, 49, 452 [J. Anal. Chem., 1994, 49 (Engl. Transl.)].Google Scholar
  4. 4.
    H. Weisz and K. A. Rotmaier, Anal. Chim. Acta, 1975, 80, 357.CrossRefGoogle Scholar
  5. 5.
    E. C. Toren and F. J. Burger, Mikrochim. Acta, 1968, 538.Google Scholar
  6. 6.
    J. Maslovskaya and T. Leszczynska, Talanta, 1985, 32, 883.CrossRefGoogle Scholar
  7. 7.
    D. Mealor and A. Townshend, Talanta, 1968, 15, 1371.CrossRefGoogle Scholar
  8. 8.
    E. P. Medyantseva, G. K. Budnikov, and S. S. Babkina, Zhurn. Analit. Khim., 1990, 45, 1386 [J. Anal. Chem. USSR, 1990, 45 (Engl. Transl.)].Google Scholar
  9. 9.
    A. Townshend and A. Vaughan, Talanta, 1970, 17, 299.CrossRefGoogle Scholar
  10. 10.
    A. Vanni and C. Des Tradis, Ann. Chimie (Paris), 1985, 75, 65.Google Scholar
  11. 11.
    M. P. Belyaev, Spravochnik maksimal’no dopustimykh kontsentratsii toksichnykh soedinenii v pishchevykh produktakh i ob"ektakh okruzhayushchei sredy [Reference Book on the Maximum Permissible Concemtrations of Toxic Compounds in Foodstuffs and Environmental Samples], Moscow, 1993, 26 (in Russian).Google Scholar
  12. 12.
    I. F. Dolmanova, T. N. Shekhovtsova, and V. V. Kutcheryaeva, Talanta, 1987, 34, 201.CrossRefGoogle Scholar
  13. 13.
    T. N. Shekhovtsova, S. V. Muginova, U. M. Migunova, and I. F. Dolmanova, Quimica Analitica, 1996, 15, 312.Google Scholar
  14. 14.
    Yu. M. Torchinskii, Sera v belkakh [Sulfur in Proteins], Nauka, Moscow, 1977, 43 (in Russian).Google Scholar
  15. 15.
    N. N. Ugarova, I. M. Popova, I. F. Dolmanova, and T. N. Shekhovtsova, Biokhimiya, 1981, 46, 1026 [Biochemistry (USSR), 1981, 46 (Engl. Transl.)].Google Scholar
  16. 16.
    S. V. Muginova, T. N. Shekhovtsova, and I. F. Dolmanova, Zhurn. Analit. Khim., 2002, 57, 1308 [J. Anal. Chem., 2002, 57 (Engl. Transl.)].Google Scholar
  17. 17.
    I. F. Dolmanova, I. M. Popova, N. N. Ugarova, and T. N. Shekhovtsova, Zhurn. Analit. Khim., 1981, 36, 1347_[J. Anal. Chem. USSR, 1981, 36 (Engl. Transl.)].Google Scholar
  18. 18.
    T. Keleti, Basic Enzyme Kinetics, Academia Kiado, Budapest, 1990, 234.Google Scholar
  19. 19.
    T. N. Shekhovtsova, S. V. Muginova, and I. F. Dolmanova, Int. J. Environm. Anal. Chem., 1998, 69, 191.CrossRefGoogle Scholar
  20. 20.
    V. M. Byr’ko, Ditiokarbamaty [Dithiocarbamates], Nauka, Moscow, 1984, 342 pp. (in Russian).Google Scholar
  21. 21.
    T. N. Shekhovtsova, A. L. Lyalyulin, E. I. Kondrat’eva, I. G. Gazaryan, and I. F. Dolmanova, Zhurn. Analit. Khim., 1994, 49, 1317 [J. Anal. Chem., 1994, 49 (Engl. Transl.)].Google Scholar
  22. 22.
    I. G. Gazaryan, D. B. Loginov, A. L. Lialulin, and T. N. Shekhovtsova, Anal. Lett., 1994, 27, 2917.Google Scholar
  23. 23.
    N. A. Bagirova, R. B. van Huystee, T. N. Shekhovtsova, and I. G. Gazarian, Talanta, 2001, 55, 1151.CrossRefGoogle Scholar
  24. 24.
    N. A. Bagirova, T. N. Shekhovtsova, N. V. Tabatchikova, and R. B. van Kh’yusti, Zhurn. Analit. Khim., 2000, 55, 93 [J. Anal. Chem., 2000, 55 (Engl. Transl.)].Google Scholar
  25. 25.
    N. A. Bagirova, T. N. Shekhovtsova, E. A. Shopova, and R. B. van Huystee, Mendeleev Commun., 1998, 4, 155.CrossRefGoogle Scholar
  26. 26.
    T. N. Shekhovtsova, S. V. Muginova, J. A. Luchinina, and A. Z. Galimova, Anal. Chim. Acta, 2006, 573, 125.CrossRefGoogle Scholar
  27. 27.
    I. F. Dolmanova, E. V. Ershova, T. N. Shekhovtsova, and V. Yu. Nad’, Zhurn. Analit. Khim., 1979, 34, 1644 [J. Anal. Chem. USSR, 1979, 34 (Engl. Transl.)].Google Scholar
  28. 28.
    T. N. Shekhovtsova, N. N. Starodumova, and I. F. Dolmanova, Zhurn. Analit. Khim., 1987, 42, 1824 [J. Anal. Chem. USSR, 1987, 42 (Engl. Transl.)].Google Scholar
  29. 29.
    T. N. Shekhovtsova, N. A. Bagirova, I. A. Veselova, and S. V. Muginova, Radionuclides and Heavy Metals in Environment, Kluwer Academic Publishers, Amsterdam, 2001, 201.Google Scholar
  30. 30.
    T. N. Shekhovtsova, S. V. Chernetskaya, and I. F. Dolmanova, Zhurn. Analit. Khim., 1993, 48, 129 [J. Anal. Chem., 1993, 48 (Engl. Transl.)].Google Scholar
  31. 31.
    T. N. Shekhovtsova, Egypt. J. Anal. Chem., 2000, 9, 11.Google Scholar
  32. 32.
    E. V. Zhmaeva, P. V. Bychkov, and T. N. Shekhovtsova, Vestnik MGU, Ser. Khimiya, 2002, 6, 404 [Vestn. Mosc. Univ., Ser. Khim., 2002, 6 (Engl. Transl.)].Google Scholar
  33. 33.
    E. V. Zhmaeva and T. N. Shekhovtsova, Zhurn. Analit. Khim., 2000, 55, 869 [J. Anal. Chem., 2000, 55 (Engl. Transl)].Google Scholar
  34. 34.
    P. V. Bychkov, T. N. Shekhovtsova, and E. R. Milaeva, Bioinorg. Chem. Appl., 2005, 3, 191.CrossRefGoogle Scholar
  35. 35.
    T. N. Shekhovtsova and E. V. Zhmaeva, Microchim. Acta, 2002, 140, 295.CrossRefGoogle Scholar
  36. 36.
    P. Bychkov and T. Shekhovtsova, Mendeleev Commun., 2003, 1, 75.Google Scholar
  37. 37.
    S. V. Muginova, A. M. Zhavoronkova, and T. N. Shekhovtsova, Zhurn. Analit. Khim., 2005, 60, 247 [J. Anal. Chem., 2005, 60 (Engl. Transl)].Google Scholar
  38. 38.
    A. M. Zhavoronkova, S. V. Muginova, I. A. Veselova, and T. N. Shekhovtsova, Zhurn. Analit. Khim., 2003, 58, 88 [J. Anal. Chem., 2003, 58 (Engl. Transl)].Google Scholar
  39. 39.
    A. M. Zhavoronkova, S. V. Muginova, and T. N. Shekhovtsova, Zhurn. Analit. Khim., 2005, 60, 425 [J. Anal. Chem., 2005, 60 (Engl. Transl)].Google Scholar
  40. 40.
    A. M. Zhavoronkova, S. V. Muginova, and T. N. Shekhovtsova, Vestnik MGU, Ser. Khim., 2003, 44, 123 [Vestn. Mosc. Univ., Ser. Khim., 2003, 44 (Engl. Transl.)].Google Scholar
  41. 41.
    S. V. Muginova, A. M. Zhavoronkova, A. E. Polyakov, and T. N. Shekhovtsova, Anal. Sci., 2007, 23, 357.CrossRefGoogle Scholar
  42. 42.
    T. N. Shekhovtsova, I. L. Mityureva, M. V. Shvetskaya, and I. F. Dolmanova, Zhurn. Analit. Khim., 1991, 46, 571_[J. Anal. Chem. USSR, 1991, 46 (Engl. Transl)].Google Scholar
  43. 43.
    T. N. Shekhovtsova, S. V. Chernetskaya, N. V. Belkova, and I. F. Dolmanova, Zhurn. Analit. Khim., 1994, 49, 789 [J. Anal. Chem., 1994, 49 (Engl. Transl)].Google Scholar
  44. 44.
    I. A. Veselova, T. N. Shekhovtsova, and G. A. Badun, Vseros. nauch. konf. “Novye perspektivy v issledovanii khitina i khitozana” [All-Russian Scientific Conf. “New Prospects in the Research of Chitin and Chitosan], Abstrs. (Shchelkovo, March 11–14, 1999), Moscow, 1999, 265–267 (in Russian).Google Scholar
  45. 45.
    S. V. Muginova, I. A. Veselova, and T. N. Shekhovtsova, Zh. Prikl. Khim., 1999, 72, 803 [Russ. J. Appl. Chem., 1999, 72 (Engl. Transl)].Google Scholar
  46. 46.
    I. F. Dolmanova, T. N. Shekhovtsova, and M. K. Beklemishev, Zhurn. Analit. Khim., 2002, 57, 1043_[J. Anal. Chem., 2002, 57 (Engl. Transl)].Google Scholar
  47. 47.
    T. N. Shekhovtsova, S. V. Chernetskaya, E. B. Nikol’skaya, and I. F. Dolmanova, Zhurn. Analit. Khim., 1994, 49, 862 [J. Anal. Chem., 1994, 49 (Engl. Transl)].Google Scholar
  48. 48.
    T. N. Shekhovtsova and S. V. Chernetskaya, Anal. Lett., 1994, 27, 2883.Google Scholar
  49. 49.
    I. A. Veselova, Ph.D. Thesis, M. V. Lomonosov Moscow State University, Moscow, 2001, 295 pp. (in Russian).Google Scholar
  50. 50.
    T. N. Shekhovtsova, S. V. Chernetskaya, N. V. Belkova, and I. F. Dolmanova, Zhurn. Analit. Khim., 1995, 50, 538 [J. Anal. Chem., 1995, 50 (Engl. Transl)].Google Scholar
  51. 51.
    S. V. Muginova, N. A. Akovbyan, T. N. Shekhovtsova, and I. F. Dolmanova, Zhurn. Analit. Khim., 1999, 54, 645 [J. Anal. Chem., 1999, 54 (Engl. Transl)].Google Scholar
  52. 52.
    I. A. Veselova and T. N. Shekhovtsova, Anal. Chim. Acta, 1999, 392, 151.CrossRefGoogle Scholar
  53. 53.
    I. A. Veselova and T. N. Shekhovtsova, Mendeleev Commun., 2000, 6, 98.Google Scholar
  54. 54.
    T. N. Shekhovtsova, S. V. Muginova, and N. A. Bagirova, Anal. Chim. Acta, 1997, 344, 145.CrossRefGoogle Scholar
  55. 55.
    I. A. Veselova and T. N. Shekhovtsova, Anal. Chim. Acta, 2000, 413, 95.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • T. N. Shekhovtsova
    • 1
  • S. V. Muginova
    • 1
  • I. A. Veselova
    • 1
  1. 1.Department of ChemistryM. V. Lomonosov Moscow State UniversityMoscowRussian Federation

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