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Russian Chemical Bulletin

, Volume 54, Issue 11, pp 2642–2647 | Cite as

Synthesis of 1,2-azaphospholanes containing an amino acid fragment

  • O. V. Bykhovskaya
  • I. M. Aladzheva
  • D. I. Lobanov
  • P. V. Petrovskii
  • K. A. Lyssenko
  • I. V. Fedyanin
  • T. A. Mastryukova
Article

Abstract

2-Oxo-1,2-azaphospholanes and 1,2-azaphospholanium salts containing an amino acid fragment were synthesized by intramolecular P-alkylation of N-3-chloropropyl-substituted tricoordinate phosphorus amides. Hydrolysis of 2-oxo-1,2-azaphospholanes at the P-N bond gives rise to γ-aminopropylphosphonic acid derivatives.

Key words

P-alkylation Arbuzov rearrangement 2-oxo-1,2-azaphospholanes 1,2-azaphospholanium salts diastereomers hydrolysis γ-aminopropylphosphonic acid derivatives NMR spectroscopy X-ray diffraction study 

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • O. V. Bykhovskaya
    • 1
  • I. M. Aladzheva
    • 1
  • D. I. Lobanov
    • 1
  • P. V. Petrovskii
    • 1
  • K. A. Lyssenko
    • 1
  • I. V. Fedyanin
    • 1
  • T. A. Mastryukova
    • 1
  1. 1.A. N. Nesmeyanov Institute of Organoelement CompoundsRussian Academy of SciencesMoscowRussian Federation

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