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Russian Chemical Bulletin

, Volume 54, Issue 3, pp 738–742 | Cite as

Synthesis of thieno[3.2-b]pyrrolenine derivatives under the Fischer reaction conditions

  • V. Z. Shirinian
  • M. M. Krayushkin
  • D. M. Nikalin
  • A. A. Shimkin
Article

Abstract

The reaction of alkyl 4-(2-acetylhydrazino)-2-methyl-3-thiophenecarboxylates with 3-methylbutan-2-one was carried out under the Fischer reaction conditions. The influence of Lewis acids and solvents on the process was studied. A convenient method for the synthesis of thieno [3.2-b]pyrrolenine derivatives was proposed.

Key words

thieno[3,2-b]pyrrolenines 3-methylbutan-2-one Fischer reaction β-thienylhydrazine benzidine rearrangement Lewis acids 

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • V. Z. Shirinian
    • 1
  • M. M. Krayushkin
    • 1
  • D. M. Nikalin
    • 1
  • A. A. Shimkin
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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