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Convenient synthesis of drimenol and its oxidation with selenium dioxide

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Abstract

A convenient synthesis of drimenol by treatment of readily available drimane-8α, 11-diol 11-monoacetate with sulfuric acid in ethanol under mild conditions was developed. Oxidation of drimenol with selenium dioxide gives known drim-7-ene-9α, 11-diol and drim-7-ene-11,12-diol as the major products.

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Authors and Affiliations

  1. Institute of Chemistry, Academy of Sciences of the Republic of Moldova, 3 ul. Academiei, MD-2028, Kishinev, Republic of Moldova

    K. I. Kuchkova, A. N. Aricu, I. P. Dragalin & P. F. Vlad

Authors
  1. K. I. Kuchkova
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  2. A. N. Aricu
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  3. I. P. Dragalin
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  4. P. F. Vlad
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2745–2748, December, 2004.

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Kuchkova, K.I., Aricu, A.N., Dragalin, I.P. et al. Convenient synthesis of drimenol and its oxidation with selenium dioxide. Russ Chem Bull 53, 2862–2865 (2004). https://doi.org/10.1007/s11172-005-0203-x

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  • DOI: https://doi.org/10.1007/s11172-005-0203-x

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