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Russian Journal of Bioorganic Chemistry

, Volume 31, Issue 3, pp 256–262 | Cite as

Polymethylene Derivatives of Nucleic Bases with ω-Functional Groups: IV. [7-(2-Oxocyclohexyl)-7-oxoheptyl]purines

  • A. M. Kritzyn
  • J. Vepsalainen
  • V. V. Komissarov
Article

Abstract

New polymethylene nucleoside analogues with a β-dioxo function in the ω-position of their hydro-carbon chain, [7-(2-oxocyclohexyl)-7-oxoheptyl]purines, were synthesized, and their physicochemical properties were studied.

Key words

alkylation nucleosides polymethylene analogues 

Abbreviations

DBU

1,8-diazabicyclo[5.4.0]undec-7-ene

HSV

herpes simplex virus

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Copyright information

© MAIK “Nauka/Interperiodica” 2005

Authors and Affiliations

  • A. M. Kritzyn
    • 1
  • J. Vepsalainen
    • 2
  • V. V. Komissarov
    • 1
  1. 1.Engelhardt Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia
  2. 2.Department of ChemistryUniversity of KuopioKuopioFinland

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