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β-Enaminones over recyclable nano-CoFe2O4: a highly efficient solvent-free green protocol

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Abstract

β-Enaminone and its derivatives have emerged among the finest bioactive intermediates. High yields of several β-enaminones (86–97%) are achieved through treatment of substituted aromatic and aliphatic amines with cyclic/acyclic 1,3-diketones, over the magnetically separable cobalt ferrite nanoparticles (CoFe2O4 NPs). The latter was prepared upon co-precipitation. Its purity, fine crystallinity, elemental distributions, morphology, magnetic features, and thermal stability were confirmed by Fourier transform infrared, X-ray diffraction, energy dispersive X-ray spectrometry, scanning electron microscopy, vibrating sample magnetometry, and thermal gravimetric analysis analyses. Thus, CoFe2O4 NPs acted as an excellent green heterogeneous nanocatalyst for synthesis of β-enaminones and gave good recyclability, while showing insignificant loss of their activity.

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Author notes

  1. Mohamad Z. Kassaee: Visiting scholar (sabbatical).

Authors and Affiliations

  1. Department of Chemistry, Tarbiat Modares University, P.O. Box 14155-175, Tehran, Iran

    Esmaiel Eidi & Mohamad Z. Kassaee

  2. Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 37211, USA

    Mohamad Z. Kassaee & Peter T. Cummings

Authors
  1. Esmaiel Eidi
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  2. Mohamad Z. Kassaee
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  3. Peter T. Cummings
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Correspondence to Mohamad Z. Kassaee.

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Eidi, E., Kassaee, M.Z. & Cummings, P.T. β-Enaminones over recyclable nano-CoFe2O4: a highly efficient solvent-free green protocol. Res Chem Intermed 44, 5787–5799 (2018). https://doi.org/10.1007/s11164-018-3454-5

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