Research on Chemical Intermediates

, Volume 43, Issue 2, pp 755–765 | Cite as

Magnetically recoverable nano-zirconium(IV) complex: enhancement of antibacterial activity

  • Narjes Tayyebi Sabet Khomami
  • Felora Heshmatpour


In this study, antibacterial activity of a zirconium(IV)–Schiff base ligand [Schiff base = N,N′-bis(3-salicylidenaminopropyl)amine] was examined via the paper disk diffusion method against Escherichia coli (gram-negative bacterium) and Bacillus subtilis (gram-positive bacterium). In the next step, a magnetically recoverable analog of this compound was synthesized by covalent grafting of the Schiff base ligand onto modified silica-coated magnetic nanoparticles. The synthesis was accomplished by the complexation of these magnetically recoverable nanoparticles with Zr(acac)4. The newly synthesized particles were characterized by FT-IR, XRD, TGA–DSC, XRF, TEM, FE-SEM, and VSM, and then screened against bacteria. The results indicated the significant increased activity of zirconium complex grafted onto nanomagnetite particles. Moreover, as the particles were superparamagnetic, they could be easily recovered from the reaction matrix by use of a permanent magnet.


Zirconium Schiff base Antibacterial activity Magnetic nanoparticles 



We want to thank the K. N. Toosi University of Technology for its support.


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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • Narjes Tayyebi Sabet Khomami
    • 1
  • Felora Heshmatpour
    • 1
  1. 1.Department of ChemistryK. N. Toosi University of TechnologyTehranIran

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