Research on Chemical Intermediates

, Volume 42, Issue 7, pp 6221–6229 | Cite as

Poly(vinylpyrrolidonium) perchlorate catalyzed one-pot synthesis of tricyclic dihydropyrimidine derivatives

  • Masoumeh Abedini
  • Farhad Shirini
  • Maryam Mousapour
  • Omid Goli Jolodar


A simple and efficient procedure for the synthesis of benzo[4,5]imidazo[1,2-α]pyrimidine and 2-amino-4-substituted-1,4-dihydrobenzo[4,5]imidazolo[1,2-α]pyrimidine-3-carbonitrile derivatives using poly(vinylpyrrolidonium) perchlorate {[PVPH]ClO4} as a newly reported, modified polymeric catalyst is reported. Some of the advantages of this novel synthetic method are: easy preparation of the catalyst, simple and easy work-up procedure, short reaction times, high to excellent yields of the products and reusability of the catalyst.


Benzo[4,5]imidazo[1,2-α]pyrimidines 2-Amino-4-substituted-1,4- dihydrobenzo[4,5]imidazolo[1,2-α]pyrimidine-3-carbonitriles Poly(vinylpyrrolidonium) perchlorate {[PVPH]ClO4Heterogeneous reaction conditions Polymer-based catalyst 



We are thankful to the University of Guilan Research Council for the partial support of this work.


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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  1. 1.Department of Chemistry, College of ScienceUniversity of GuilanRashtIslamic Republic of Iran

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