MCM-41-SO3H: an efficient, reusable, heterogeneous catalyst for the one-pot, three-component synthesis of pyrano[3,2-b]pyrans

  • Yaghoub Sarrafi
  • Ebrahim Mehrasbi
  • Seyyedeh Zohreh Mashalchi


MCM-41-SO3H, ordered mesoporous silica material MCM-41 with covalently anchored sulfonic acid groups, was used as a solid acid catalyst for the convenient, efficient, and ‘green’ synthesis of 2-amino-6-(hydroxymethyl)-8-oxo-4-aryl-4,8-dihydropyrano[3,2-b]pyrans via a one-pot, three-component reaction of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one, aldehydes and malononitrile in aqueous media.


2-Amino-6-(hydroxymethyl)-8-oxo-4-aryl-4 8-Dihydropyrano[3,2-b]pyran MCM-41-SO3Multicomponent reactions Aqueous media 



The financial support from University of Mazandaran is gratefully acknowledged.

Compliance with ethical standards

We confirm that the manuscript has been submitted solely to this journal and is not published, in press, or submitted elsewhere. We confirm that all the research meets the ethical guidelines, including adherence to the legal requirements of the study country.

Conflicts of interest

We certify that we have no affiliation with or financial involvement with any organization or entity with a direct financial or any other interest in the subject matter or materials discussed in the manuscript. We declare no conflicts of interest.


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Yaghoub Sarrafi
    • 1
  • Ebrahim Mehrasbi
    • 1
  • Seyyedeh Zohreh Mashalchi
    • 1
  1. 1.Faculty of ChemistryUniversity of MazandaranBabolsarIran

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