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Simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified graphene nanosheets paste electrode

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Abstract

The electrooxidation of norepinephrine (NE) at the surface of a modified graphene nanosheet paste electrode was studied using electrochemical approaches. Under the optimized conditions (pH 7.0), the square wave voltammetric (SWV) peak current of NE increased linearly with NE concentration in the range of 8.0 × 10−8–6.0 × 10−4 M. The detection limit was 3.0 × 10−8 M for NE. This method was also used for the simultaneous determination of NE, acetaminophen (AC) and tryptophan (TRP). Finally, this new sensor was used for determination of NE, AC and TRP in some real samples.

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Authors and Affiliations

  1. Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

    Hadi Mahmoudi Moghaddam & Gholamreza Dehghan Noudeh

  2. Environmental Health Engineering Research Center and Department of Environmental Health, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran

    Hadi Mahmoudi Moghaddam

  3. Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

    Hadi Beitollahi

  4. Department of Chemistry, Shahid Bahonar University of Kerman, P.O. Box 76175-133, Kerman, Iran

    Somayeh Tajik

  5. Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran

    Hassan Karimi Maleh

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  1. Hadi Mahmoudi Moghaddam
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Correspondence to Hadi Beitollahi.

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Moghaddam, H.M., Beitollahi, H., Tajik, S. et al. Simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified graphene nanosheets paste electrode. Res Chem Intermed 41, 6885–6896 (2015). https://doi.org/10.1007/s11164-014-1785-4

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  • DOI: https://doi.org/10.1007/s11164-014-1785-4

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