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Research on Chemical Intermediates

, Volume 41, Issue 9, pp 6141–6148 | Cite as

Synthesis of bioactive substituted pyrazolylbenzothiazinones

  • Praveen Kumar Sharma
  • M. Kumar
Article

Abstract

Pyrazolylbenzothiazinones have been synthesized in good yields by the reaction of 2-hydrazinocarbonymethyl-3,4-dihydro-2H-1,4-benzothiazin-3-ones with β-diketone in the presence of ethanol. The structures of synthesized pyrazolylbenzothiazinones were confirmed on the basis of their analytical and spectral data. The antimicrobial activities of the synthesized compounds have also been included.

Keywords

Pyrazolylbenzothiazinones Benzothiazinones 2-aminobenzenethiol Antibacterial activities 

Notes

Acknowledgments

The authors are thankful to the Head, Department of Chemistry, University of Rajasthan, Jaipur (India) for providing necessary laboratory facilities as well as instrumentation facilities (IR, and 1HNMR). The Director RSIC, CDRI, Lucknow (India) is acknowledged for providing mass spectra of the synthesized compounds. We express our thanks to University Grant Commission, New Delhi, for providing meritorious student fellowship to one of us (P.K.S.).

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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.Department of ChemistryLovely Professional UniversityPhagwaraIndia
  2. 2.Department of ChemistryUniversity of RajasthanJaipurIndia

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