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Research on Chemical Intermediates

, Volume 41, Issue 2, pp 927–933 | Cite as

An efficient and eco-friendly synthesis of quinolinyl chalcones under solvent-free conditions at room temperature

  • Dinesh Sharma
Article

Abstract

A simple, rapid and eco-friendly procedure for the synthesis of quinolinyl chalcones involving grinding of quinoline-3-carbaldehydes and acetophenones with anhydrous barium hydroxide (C-200) at room temperature under solvent-free conditions has been described. The protocol is much more efficient as the reactions are carried out at room temperature, and yields are also quite high, and the use of hazardous chemicals and organic solvents at any stage of the reaction is also avoided.

Keywords

Quinolinyl chalcones Quinoline-3-carbaldehydes Eco-friendly C-200 Grinding technique 

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Department of ChemistryBRCM College of Engineering and TechnologyBahalIndia

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