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Research on Chemical Intermediates

, Volume 39, Issue 4, pp 1917–1926 | Cite as

Microwave-assisted, Ir-catalyzed aromatic C–H borylation

  • Li Zeqing
  • Liang Zhibin
  • Wang Yuqiang
  • Yu Pei
Article

Abstract

One-step conversions of 1,3-disubstituted benzenes to aryl boronates and 2,6-disubstituted pyridines to heteroaryl boronates are described. Microwave heating was used for all reactions. [(COD)Ir(μ-OMe)]2 and 4,4′-di-tert-butyl-2,2′-bipyridine were used as catalysts, in methyl tert-butyl ether. Acceleration of the rate of reaction was remarkable compared with that of same reaction under conventional heating conditions.

Keyword

Microwave heating [(COD)Ir(μ-OMe)]2 Dtbpy Pinacol boronates 

Notes

Acknowledgments

The authors acknowledge the generous support of this study by Sundia MediTech Company Ltd.

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Li Zeqing
    • 1
  • Liang Zhibin
    • 1
  • Wang Yuqiang
    • 1
    • 2
  • Yu Pei
    • 1
    • 2
  1. 1.College of Pharmacy, Institute of New Drug ResearchJinan UniversityGuangzhouChina
  2. 2.Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug ResearchGuangzhouChina

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