Reaction Kinetics, Mechanisms and Catalysis

, Volume 99, Issue 2, pp 391–396 | Cite as

Synthesis of polyethylene glycol supported chiral monosulfonamide and its application in asymmetric transfer hydrogenation of prochiral ketones



A new polyethylene glycol supported chiral monosulfonamide was conveniently synthesized from (R,R)-1,2-diphenylethylenediamine. The ruthenium catalyst prepared from polyethylene glycol supported chiral monosulfonamide with [RuCl2(p-cymene)]2 was used in the asymmetric transfer hydrogenation of prochiral ketones in neat water with good to excellent conversions and enantioselectivities. The catalyst could be easily recovered and reused several times.


Asymmetric transfer hydrogenation Chiral monosulfonamide Water Ketones 



Financial support of this work by the Natural Science Foundation of Hubei Province (2007ABA291) is gratefully acknowledged.


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2009

Authors and Affiliations

  1. 1.Key Laboratory of Catalysis and Materials Science of Hubei Province, College of Chemistry and Materials ScienceSouth-Central University for NationalitiesWuhanChina

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