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Quality of Life Research

, Volume 23, Issue 3, pp 927–938 | Cite as

Validity, reliability and discriminative capacity of an electronic quality of life instrument (Pelican) for childhood asthma in the Netherlands

  • S. van Bragt
  • L. van den Bemt
  • B. Thoonen
  • J. Jacobs
  • P. Merkus
  • T. Schermer
Article

Abstract

Purpose

To assess psychometric properties of the Pelican instrument, an online Dutch self-administered Quality of Life instrument for childhood asthma for scientific and clinical use.

Methods

A cohort study was done in two asthma populations and healthy children. One asthma population had assessment at start, 4 and 8 weeks. The other asthma population and healthy children had one assessment. All children were aged 6–12 years. Children completed the Pelican instrument, Paediatric Asthma Quality of Life Questionnaire, feeling thermometer and Childhood Asthma Control Test. Lung function and fraction exhaled nitric oxide were measured. Parents completed Functional Status II, Asthma Control Questionnaire, Childhood Asthma Control Test questionnaires and symptom diaries. We assessed interpretability, structural validity, internal consistency, reliability, construct and discriminative validity of the Pelican instrument.

Results

Eighty-five asthmatic (mean age 8.5 years) and 49 healthy children (mean age 8.4 years) participated. The Pelican instrument has 5 domains with 21 items after factor analysis. Internal consistency was 0.89 (CI 0.85–0.92), domain reliability showed Cronbach’s α’s from 0.64 to 0.76 and item-to-scale correlations from 0.61 to 0.81. Test–retest reliability was confirmed ICC = 0.88 (CI 0.79–0.93). Construct validity was demonstrated by significant moderate correlations with other relevant asthma outcomes like PAQLQ (r = −0.59, p < 0.01). Discriminative capacity between controlled or uncontrolled asthma (t = 3.20, p < 0.01, Δ = 0.64) and asthma versus healthy subjects (t = 6.31, p < 0.01, Δ = 0.94) was found.

Conclusions

The psychometric properties of the Pelican instrument were acceptable in Dutch paediatric asthma patients between 6 and 12 years old.

Keywords

Psychometric properties Asthma Children Health-related Quality of Life (HRQL) Reliability Validity 

Abbreviations

ACQ

Asthma Control Questionnaire

ATS

American Thoracic Society

CAQ-B

Childhood Asthma Questionnaire

C-ACT

Childhood Asthma Control Test

CBCL/6-18

Child Behaviour Checklist for children aged 6–18 years

ERS

European Respiratory Society

FeNO

Fraction exhaled Nitric Oxide

FEV1

Forced expiratory volume in one second

FSII

Functional Status II

FVC

Forced vital capacity

GP

General practitioner

HAY

How Are You

HRQL

Health-related quality of life

ICC

Inter-class correlation

PAQLQ

Paediatric Asthma Quality of Life Instrument

Pelican

Paediatric Electronic quality of Life Instrument for Childhood Asthma instrument in the Netherlands

PedQL

Pediatric Quality of Life Inventory

Notes

Acknowledgments

This study was financially supported by the Dutch Lung Foundation (previously Dutch Asthma Foundation). The authors would like to thank all participating children and their parents. We are also grateful to all general practitioners, pharmacists and others who helped recruiting participants and to J. Braspenning, V. Hulsman and P. Madge for the English translation process of the Pelican instrument. Moreover, we would like to thank the ‘Stichting Huisartsenlaboratorium’ (SHL), a regional diagnostic centre, for their help with the data collection. A special thanks goes to Nicol Orbon and Joke Grootens who managed the data collection of this study. Finally, we would like to thank Amadea Gloudemans (AG) and Sabine Wendt (SW), who interviewed the children and helped coding and analysing the interviews with participating children.

Conflict of interest

The authors declare that they have no competing interests.

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • S. van Bragt
    • 1
  • L. van den Bemt
    • 1
  • B. Thoonen
    • 1
  • J. Jacobs
    • 2
  • P. Merkus
    • 3
  • T. Schermer
    • 1
  1. 1.Department of Primary and Community CareRadboud University Nijmegen Medical Centre (RUNMC)NijmegenThe Netherlands
  2. 2.IQ Health CareRadboud University Nijmegen Medical Centre (RUNMC)NijmegenThe Netherlands
  3. 3.Division of Respiratory Medicine, Department of PaediatricsRadboud University Nijmegen Medical Centre (RUNMC)NijmegenThe Netherlands

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