Quality of Life Research

, Volume 22, Issue 2, pp 403–407 | Cite as

Feasibility, reliability and validity of the Chinese simplified version of the MOS-HIV health survey among AIDS patients in China

  • Zhang-Jun Huang
  • Min Tian
  • Se-Ying Dai
  • Dong-Qing Ye
Brief Communication



To test the feasibility, reliability and validity of the Chinese simplified version of the MOS-HIV health survey among AIDS patients in China.


A cross-sectional survey of 120 patients receiving highly active antiretroviral treatment was conducted. Feasibility was assessed using the time of administration and the response rate. Reliability was estimated using Cronbach’s α. Validity was analyzed by construct and discriminant validity.


The time of administration was about 12 min, and the response rate was 100%. The MOS-HIV showed a good internal reliability and Cronbach’s α of eight multi-item scales ranged from 0.75 to 0.91. Correlations between scales were all significant. The majority of the correlations between pairs of scales were within the acceptable range (0.4–0.8). The scores of role function, pain, physical health summary scales were significantly higher for patients with time on antiretroviral treatment >1 year compared to those with time ≤1 year. Patients >40 years had significantly higher scores than those of ≤40 years on energy and mental health summary scales.


The Chinese simplified version of MOS-HIV health survey had good feasibility, reliability and validity. It was successfully adapted for AIDS patients in rural areas and could be a valuable tool in evaluating the quality of life of AIDS patients.


Feasibility Reliability Validity MOS-HIV AIDS China 



Human immunodeficiency virus


Acquired immuno deficiency syndrome


Highly active antiretroviral treatment


Antiretroviral treatment


Health-related quality of life


Quality of life


Medical Outcomes Study HIV health survey


People living with HIV and AIDS



The authors wish to acknowledge all respondents in this study and Wang-dong Xu and Mo Zhou for their assistance in study preparation and the collection, processing and inputting of data. In addition, special thanks to the staff of the Center for Disease Control and Prevention of Linquan Country for their advice and help in the coordination and implementation of the study. The research was supported by the Global Fund for AIDS program in Anhui, China (CHN-607-G10-H).

Conflict of interest

The authors have no conflicts of interest.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Zhang-Jun Huang
    • 1
    • 2
  • Min Tian
    • 1
    • 2
  • Se-Ying Dai
    • 1
    • 2
  • Dong-Qing Ye
    • 1
    • 2
  1. 1.Department of Epidemiology and Biostatistics, School of Public HealthAnhui Medical UniversityHefeiPeople’s Republic of China
  2. 2.Anhui provincial laboratory of population health & major disease screening and diagnosisAnhui Medical UniversityHefeiPeople’s Republic of China

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