Quality of Life Research

, Volume 21, Issue 9, pp 1587–1594 | Cite as

The effect of family-based multidisciplinary cognitive behavioral treatment on health-related quality of life in childhood obesity

  • Rimke C. Vos
  • Sasja D. Huisman
  • Euphemia C. A. M. Houdijk
  • Hanno Pijl
  • Jan M. Wit



To evaluate the effect of multidisciplinary treatment on obesity and health-related quality of life (HRQOL).


Obese children were randomized to a multidisciplinary lifestyle treatment, including medical, nutritional, physical, and psychological counseling during 3 months, (n = 40, BMI-SDS; 4.2 ± 0.7, age; 13.3 ± 2.0) or standard care, including an initial advice on nutrition and physical activity by the pediatrician (n = 39, BMI-SDS; 4.3 ± 0.7, age; 13.1 ± 1.9). At baseline, after 3 months of treatment and at 12 months follow-up, data were collected for BMI-SDS and a European validated questionnaire for assessing HRQOL (DISABKIDS).


A significantly reduced BMI-SDS was found for the intervention group after 3 months treatment (4.0 ± 0.9 vs. 4.2 ± 0.7, P = 0.02) and at 12 months follow-up (3.8 ± 1.1 vs. 4.2 ± 0.7, P = 0.03). HRQOL in the intervention group was significantly improved at 12 months follow-up and unchanged in the obese control group. Agreement between child and parent report was moderate (67–85%), with parents reporting a lower HRQOL for their obese children than children themselves in both groups.


Multidisciplinary treatment is effective in reducing BMI-SDS and improving HRQOL after 12 months follow-up.


Health-related quality of life Obesity Children Adolescents Treatment Parents 



Body mass index


Body mass index standard deviation score


Health-related quality of life


Inter-class correlation coefficient


German questionnaire for measuring quality of life in children and adolescents


Pediatric quality of life inventory


Pictorial representation of illness and self measure


Quality of life



The study was partly funded by an unrestricted educational grant by Pfizer and an unrestricted educational grant by a non-profit foundation (“de Stichting Vrienden van het JKZ”). We acknowledge and appreciated the helpful advice about the DISABKIDS questionnaire by Dr. H.M. Koopman. We also thank N. Kist for her help with implementing data for analysis. In addition, we thank all members of the multidisciplinary team for their time and patience in treating the children, and the participating children and their families.

Conflict of interest

All authors declare no conflict of interest.


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Rimke C. Vos
    • 1
  • Sasja D. Huisman
    • 2
  • Euphemia C. A. M. Houdijk
    • 1
  • Hanno Pijl
    • 3
  • Jan M. Wit
    • 4
  1. 1.Department of PediatricsJuliana Children’s Hospital/ HagaHospitalThe HagueThe Netherlands
  2. 2.Department of Clinical and Health PsychologyLeiden UniversityLeidenThe Netherlands
  3. 3.Department of Endocrinology and MetabolismLeiden University Medical CenterLeidenThe Netherlands
  4. 4.Department of PediatricsLeiden University Medical CenterLeidenThe Netherlands

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