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Quality of Life Research

, Volume 19, Issue 8, pp 1127–1131 | Cite as

Quality of life of patients with oesophageal cancer in Taiwan: validation and application of the Taiwan Chinese (Mandarin) version of the EORTC QLQ-OES18: a brief communication

  • Wei-Chu Chie
  • Chia-Jih Tsai
  • Chieh Chiang
  • Yung-Chie Lee
Brief Communication

Abstract

Purpose

The aim of this study was to examine the reliability and validity, and the application of the Taiwan Chinese Version of the EORTC QLQ-OES18.

Methods

The authors translated the questionnaire according to the guideline of the EORTC. Ninety-five patients with oesophageal cancer in National Taiwan University Hospital were interviewed using the questionnaire and the EORTC QLQ-C30 between October 2002 and September 2007. Answer distribution and psychometric properties of the EORTC QLQ-OES18 were examined.

Results

The mean age of the patients was 60 years (SD 12 years). Most of the patients were in advanced stages of disease, with two-thirds off-treatment. The Cronbach’s alpha coefficients were satisfactory (0.77–0.82) or near-satisfactory (pain: 0.67). The item-to-own and item-to-other scale correlations showed satisfactory results. Patients who were on-treatment versus off-treatment had significantly poorer quality of life scores in dysphagia, dry mouth, and taste, and a borderline poorer score in cough. Opposite situations were seen in the scales of reflux and choking.

Conclusions

The EORTC QLQ-OES18 is a valid instrument to assess quality of life issues in patients with oesophageal cancer in Taiwan.

Keywords

Oesophageal cancer EORTC QLQ-C30 EORTC QLQ-OES18 Quality of life 

Notes

Acknowledgments

The authors of this study are grateful to the interviewers and for administrative assistance from the Department of Surgery and the Division of Medical Records of the National Taiwan University Hospital. Grant sponsor: The National Science Council, Taiwan, No. NSC 94-2314-B002-098, NSC95-2314-B002-266MY1, and NSC95-2314-B002-266MY2.

References

  1. 1.
    Bureau of Health Promotion, Department of Health: Cancer Registry, Taiwan, 2009. http://crs.cph.ntu.edu.tw/main.php?Page=A5.
  2. 2.
  3. 3.
    Akiyama, H., Tsurumaru, M., Udagawa, H., & Kajiyama, Y. (1997). Oesophageal cancer. Current Problems in Surgery, 34, 765–834.CrossRefPubMedGoogle Scholar
  4. 4.
    Hulscher, J. B., van Sandick, J. W., de Boer, A. G., Wijnhoven, B. P. L., Tijssen, J. G. P., Fockens, P., et al. (2002). Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. New England Journal of Medicine, 347, 1662–1669.CrossRefPubMedGoogle Scholar
  5. 5.
    Cunningham, D., Starling, N., Rao, S., Iveson, T., Nicolson, M., Coxon, F., et al. (2008). Capecitabine and oxaliplatin for advanced esophagogastric cancer. New England Journal of Medicine, 358, 36–46.CrossRefPubMedGoogle Scholar
  6. 6.
    Aaronson, N. K., Ahmedzai, A., Berman, B., et al. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85, 65–376.Google Scholar
  7. 7.
    Apolone, G., Filiberti, A., Cifani, S., Ruggiata, R., & Mosconi, P. (1998). Evaluation of the EORTC QLQ-C30 questionnaire: a comparison with SF-36 Health Survey in a cohort of Italian long-survival cancer patients. Annals of Oncology, 9, 549–557.CrossRefPubMedGoogle Scholar
  8. 8.
    McLachlan, S.-A., Devins, G. M., & Goodwin, P. J. (1998). Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) as a measure of psychosocial function in breast cancer patients. European J Cancer, 34, 510–517.CrossRefGoogle Scholar
  9. 9.
    McLachlan, S. A., Devins, G. M., & Goodwin, P. J. (1999). Factor analysis of the psychosocial items of the EORTC QLQ-C30 in metastatic breast cancer patients participating in a psychosocial intervention study. Quality of Life Research, 8, 311–317.CrossRefPubMedGoogle Scholar
  10. 10.
    Hjermstad, M. J., Fossa, S. D., Bjordal, K., & Kaasa, S. (1995). Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire. J Clin Oncology, 13, 1249–1254.Google Scholar
  11. 11.
    Groenvold, M., Klee, M. C., Sprangers, M. A. G., & Aaronson, N. K. (1997). Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement. Journal of Clinical Epidemiology, 50, 441–450.CrossRefPubMedGoogle Scholar
  12. 12.
    Chie, W. C., Hong, R. L., Lai, C. C., Ting, L. L., & Hsu, M. M. (2003). Quality of Life in Patients of Nasopharyngeal Carcinoma: Validation of the Taiwan Chinese version of the EORTC QLQ-C30 and the EORTC QLQ-H&N35. Quality of Life Research, 12, 93–98.CrossRefPubMedGoogle Scholar
  13. 13.
    Chie, W. C., Chang, K. J., Huang, C. S., & Kuo, W. H. (2003). Quality of life of breast cancer patients in Taiwan: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and EORTC QLQ-BR23. Psycho-Oncology, 12, 729–735.CrossRefPubMedGoogle Scholar
  14. 14.
    Chie, W. C., Yang, C. H., Hsu, C., & Yang, P. C. (2004). Quality of life of lung cancer patients: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-LC13. Quality of Life Research, 13, 257–262.CrossRefPubMedGoogle Scholar
  15. 15.
    Huang, C. C., Lien, H. H., Sung, Y. C., Liu, H. T., & Chie, W. C. (2007). Quality of life of patients with gastric cancer in Taiwan: Validation and clinical application of the Taiwan Chinese version of the EORTC QLQ-C30 and EORTC QLQ-STO22. Psycho-Oncology, 16, 945–949.CrossRefPubMedGoogle Scholar
  16. 16.
    Blazeby, J. M., Alderson, D., Winstone, K., Steyn, R., Hammerlid, E., Arraras, J., et al. (1996). Development of an EORTC questionnaire module to be in quality of life assessment for patients with oesophageal cancer. European Journal of Cancer, 32A, 1912–1917.CrossRefPubMedGoogle Scholar
  17. 17.
    Blazeby, J. M., Conroy, T., Hammerlid, E., Fayers, P., Sezer, O., Koller, M., et al. (2003). Clinical and psychometric validation of an EORTC questionnaire module, the EORTC QLQ-OES18, to assess quality of life in patients with oesophageal cancer. European Journal of Cancer, 39, 1384–1394.CrossRefPubMedGoogle Scholar
  18. 18.
    Blazeby, J. M., Farndon, J. R., Donovan, J., & Alderson, D. (2000). A prospective longitudinal study examining the quality of life of patients with esophageal cancer. Cancer, 88, 1781–1787.CrossRefPubMedGoogle Scholar
  19. 19.
    Lagergren, P., Avery, K. N., Hughes, R., Barham, C. P., Alderson, D., Falk, S. J., et al. (2007). Health-related quality of life among patients cured by surgery for esophageal cancer. Cancer, 110, 686–693.CrossRefPubMedGoogle Scholar
  20. 20.
    Martin, L., Lagergren, J., Lindblad, M., Rouvelas, I., & Lagergren, P. (2007). Malnutrition after oesophageal cancer surgery in Sweden. British Journal of Surgery, 94, 1496–1500.CrossRefPubMedGoogle Scholar
  21. 21.
    Bergquist, H., Johnsson, A., Hammerlid, E., Wenger, U., Lundell, L., & Ruth, M. (2008). Factors predicting survival in patients with advanced oesophageal cancer: A prospective multicentre evaluation. Alimentary Pharmacology & Therapeutics, 27, 385–395.CrossRefGoogle Scholar
  22. 22.
    Djärv, T., Blazeby, J. M., & Lagergren, P. (2009). Predictors of postoperative quality of life after esophagectomy for cancer. Journal of Clinical Oncology, 27, 1963–1968.CrossRefPubMedGoogle Scholar
  23. 23.
    Cull, A., Sprangers, M., Bjordal, K., et al. (1998). EORTC quality of life study group translation procedure. Brussels: EORTC Quality of Life Study Group.Google Scholar
  24. 24.
    Tabachnik, B. G., & Fidell, L. S. (2001). Using multivariate statistics. London: Harper & Row.Google Scholar
  25. 25.
    Osoba, D., Rodrigues, G., Myles, J., Zee, B., & Pater, J. (1998). Interpreting the significance of changes in health-related quality of life scores. Journal of Clinical Oncology, 16, 139–144.PubMedGoogle Scholar
  26. 26.
    Fayers, P., Aaronson, N., Bjordal, K., Curran, D., & Groenvold, M. (1999). EORTC QLQ-C30 scoring manual (2nd ed.). Brussels: EORTC Quality of Life Study Group.Google Scholar
  27. 27.
    Blazeby, J. M., Conroy, T., Bottomley, A., Vickery, C., Arraras, J., Sezer, O., Moore, J., Koller, M., Turhal, N. S., Stuart, R., Van Cutsem, E., D’haese, S., Coens, C., European Organisation for Research and Treatment of Cancer Gastrointestinal and Quality of Life Groups. (2004). Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-STO22, to assess quality of life in patients with gastric cancer. Eur J Cancer, 40, 2260–2268.Google Scholar
  28. 28.
    Lagergren, P., Fayers, P., Conroy, T., Stein, H. J., Sezer, O., Hardwick, R., Hammerlid, E., Bottomley, A., Van Cutsem, E., Blazeby, J. M., and on behalf of the European Organisation for Research Treatment of Cancer Gastrointestinal and Quality of Life Group. (2007). Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-OG25, to assess health-related quality of life in patients with cancer of the oesophagus, the oesophago–gastric junction and the stomach. European Journal of Cancer, 43, 2066–2073.Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Wei-Chu Chie
    • 1
  • Chia-Jih Tsai
    • 1
  • Chieh Chiang
    • 2
  • Yung-Chie Lee
    • 3
  1. 1.Department of Public Health, Graduate Institute of Preventive Medicine, College of Public HealthNational Taiwan UniversityTaipeiTaiwan, ROC
  2. 2.Division of Biostatistics and Bioinformatics, Institute of Population Health SciencesNational Health Research InstitutesChunanTaiwan, ROC
  3. 3.Department of Surgery, College of MedicineNational Taiwan UniversityTaipeiTaiwan, ROC

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