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Quality of Life Research

, Volume 17, Issue 6, pp 927–932 | Cite as

Measuring breast cancer-specific health-related quality of life in South Asia: psychometric properties of the Sinhala version of the EORTC QLQ-BR23

  • Harindra Jayasekara
  • Lalini C. Rajapaksa
  • Yvonne Brandberg
Brief Communication

Abstract

Objective

To evaluate the psychometric properties of the Sinhala version of the breast cancer-specific health-related quality of life (HRQL) module of the European Organization for Research and Treatment of Cancer (QLQ-BR23).

Methods

Psychometric testing assessed the hypothesized scale structure, internal consistency, construct validity and acceptability of the Sinhala version of the QLQ-BR23 in a consecutive series of 356 newly diagnosed breast cancer patients recruited from tertiary care oncology treatment centres in Sri Lanka.

Results

Compliance and self-completion rates were high (98% and 88%, respectively), and missing data low (0.06%). Multitrait scaling confirmed the scale structure of the QLQ-BR23 with excellent item convergence (95%), item discrimination (99%), and scaling success (99%) rates. The Cronbach’s alpha coefficients of the scales for internal consistency reliability ranged from 0.68 to 0.93. Construct validity was confirmed with satisfactory results for interscale correlations and known-groups comparisons. QLQ-BR23 item-scale correlations met or exceeded the convergent validity criterion of 0.40 for all but one item. QLQ-BR23 interscale correlations met this criterion for three comparisons and for five comparisons with conceptually related QLQ-C30 scales. Correlations between QLQ-BR23 scales and QLQ-C30 functional scales were lower as expected. As expected, most dimensions of the QLQ-BR23 were able to discriminate clearly between pretreatment and current treatment patients.

Conclusion

Overall psychometric results for the Sinhala version of the QLQ-BR23 confirmed it as a reliable and valid questionnaire for assessing breast cancer-specific HRQL in Sri Lanka.

Keywords

Breast cancer EORTC QLQ-BR23 Psychometrics Health-related quality of life 

Notes

Acknowledgements

The study was funded by the World Health Organization Country Office for Sri Lanka through Agreement for Performance of Work No SE/SRL OSD 001/RB 04/EC 1/P1/A2.

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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Harindra Jayasekara
    • 1
    • 2
  • Lalini C. Rajapaksa
    • 3
  • Yvonne Brandberg
    • 4
  1. 1.Epidemiology UnitMinistry of HealthColombo 10Sri Lanka
  2. 2.Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, School of Population HealthThe University of MelbourneCarltonAustralia
  3. 3.Department of Community Medicine, Faculty of MedicineUniversity of ColomboColombo 8Sri Lanka
  4. 4.Department of Oncology-PathologyKarolinska InstitutetStockholmSweden

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