Quality of Life Research

, Volume 15, Issue 9, pp 1519–1524 | Cite as

Brazilian version of the QLQ-LC13 lung cancer module of the European Organization for Research and Treatment of Cancer: preliminary reliability and validity report

  • Eloá Pereira Brabo
  • Marcos Eduardo Machado Paschoal
  • Irene Biasoli
  • Fernanda Esteves Nogueira
  • Magda Conceição B. Gomes
  • Isabelle Pimentel Gomes
  • Leila Cristina Andrade Martins
  • Nelson Spector


This study reports the reliability and validity of the Brazilian Portuguese version of QLQ-LC13. After translation and cross-cultural adaptation, the questionnaire was administered, together with the QLQ-C30 core questionnaire, to 82 patients with lung cancer. The analysis was based on 60 patients who completed two interviews, and who received chemotherapy alone or in combination with radiotherapy. The reliability or internal consistency of dyspnea scale was 0.79. The pain scale needed to be combined with the QLQ-C30 pain items to reach a satisfactory value of 0.73. The construct validity was supported by the ability of the questionnaire to discriminate patients regarding their performance status and type of treatment. However, the change over time, although in the expected direction for all items, was statistically significant in four of the 10 items studied. The criterion-related validity was supported by the statistically significant correlation between all four side effect items and the physicians’ reports of toxicity, while the evolutive changes in the performance status were statistically significant in only four items. Most psychometric properties of the Brazilian version of the QLQ-LC13 were adequately supported in this analysis. However, a wider utilization of this module is necessary to fully ascertain its reliability and validity properties.


Brazil EORTC QLQ-LC13 Lung cancer Quality of life 


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The authors wish to thank Ms. Karen West, from the Quality of Life Unit of the EORTC, for assistance throughout the translation and cultural adaptation phases of the study. We are also grateful to the staffs of “Cetho” and “Oncoclínica” for their kind cooperation.


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Eloá Pereira Brabo
    • 1
  • Marcos Eduardo Machado Paschoal
    • 2
  • Irene Biasoli
    • 3
  • Fernanda Esteves Nogueira
    • 4
  • Magda Conceição B. Gomes
    • 4
  • Isabelle Pimentel Gomes
    • 5
  • Leila Cristina Andrade Martins
    • 6
  • Nelson Spector
    • 3
  1. 1.Oncology Service, University HospitalFederal University of Rio de JaneiroRio de JaneiroBrazil
  2. 2.Pneumology ServiceInstitute of Thoracic Diseases, Federal University of Rio de JaneiroRio de JaneiroBrazil
  3. 3.Hematology ServiceUniversity Hospital and School of Medicine, Federal University of Rio de JaneiroRio de JaneiroBrazil
  4. 4.Resident from the Oncology ServiceUniversity Hospital, Federal University of Rio de JaneiroRio de JaneiroBrazil
  5. 5.Chemotherapy Unit from CETHORio de JaneiroBrazil
  6. 6.Chemotherapy Unit from OncoclínicaRio de JaneiroBrazil

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