Quality of Life Research

, Volume 15, Issue 2, pp 233–248 | Cite as

Evaluation of Cross-sectional and Longitudinal Construct Validity of Two Vision-related Quality of Life Questionnaires: The LVQOL and VCM1

  • M. R. de Boer
  • C. B. Terwee
  • H. C. W. de Vet
  • A. C. Moll
  • H. J. M Völker-Dieben
  • G. H. M. B. van Rens
Instrument Development and Evaluation


The Low Vision Quality of Life (LVQOL) questionnaire and the Vision-related Quality of Life Core Measure (VCM1) are two of the many vision-related quality of life (QOL) questionnaires that have been developed in recent years. Although psychometric properties of the LVQOL and VCM1 compare well with other vision-related QOL questionnaires, construct and longitudinal validity have not been assessed (adequately). The purpose of this study was to examine the cross-sectional and longitudinal construct validity of these questionnaires by testing specific pre-specified hypotheses about the relations of these questionnaires with other measures. The percentage of hypotheses regarding the cross-sectional construct validity that were refuted for the LVQOL was 22% for the basic aspects of vision subscale, 50% for the mobility subscale, 39% for the adjustment subscale and 17% for the reading and fine work subscale. For the VCM1 this percentage was 57%. For the longitudinal construct validity the percentage of hypotheses that were refuted ranged from 33 to 75% for the LVQOL subscales and was 50% for the VCM1. In conclusion, cross-sectional construct validity was satisfactory for the LVQOL subscales, but seemed poor for the VCM1. In addition, the longitudinal validity of these scales was poor to moderate.


Health-related quality of life Questionnaires Visually impaired persons 



confirmatory factor analysis


comparative fit index


confidence interval


global rating question


Health Assessment Questionnaire


health-related quality of life


intra-class correlation coefficient




standard deviation


Low Vision Quality of Life questionnaire


quality of life


Vision-related Quality of Life Core Measure


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Copyright information

© Springer 2006

Authors and Affiliations

  • M. R. de Boer
    • 1
    • 2
    • 4
  • C. B. Terwee
    • 2
  • H. C. W. de Vet
    • 2
  • A. C. Moll
    • 1
    • 2
  • H. J. M Völker-Dieben
    • 1
  • G. H. M. B. van Rens
    • 1
    • 2
    • 3
  1. 1.Department of OphthalmologyVU University Medical CenterAmsterdamThe Netherlands
  2. 2.Institute for Research in Extramural MedicineVU University Medical CenterAmsterdamThe Netherlands
  3. 3.Elkerliek HospitalHelmondThe Netherlands
  4. 4.Department of OphthalmologyVU University Medical CenterAmsterdamThe Netherlands

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