Free and bound phenolics extracts from nejayote solids were obtained after optimally lime-cooking blue, normal white, red, normal yellow, high-carotenoid and quality protein maize types. The extraction yield ranged from 4.47 to 10.05%. Bound phenolics extracts had higher content of total phenolics, antioxidant activity and ferulic acid compared to the free phenolics extracts. In general, free phenolics extracts were less cytotoxic than the bound phenolics counterparts. Bound phenolics extracts had higher induction of quinone reductase (QR) and particularly the normal yellow nejayote exerted the highest chemopreventive index tested in Hepa1c1c7 cells. When tested for monofunctional phase 2 induction capacity in BPrc1 cells, the bound phenolics extracts of blue, normal white and quality protein nejayotes were better inducers than the normal yellow counterpart. Particularly, the free phenolics extract of the white maize nejayote induced BPrc1 cells QR and exerted a higher chemopreventive index compared to the bound phenolics extract. Therefore, the nejayote of the normal white maize was the best source of monofunctional phase 2 enzyme inducers.
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This research was supported by the Research Chair Funds CAT-005 from Tecnológico de Monterrey-Campus Monterrey. The six contrasting types of maize were kindly donated by CIMMYT’s Global Maize Program (Batan Experimental Station, Mexico).
Salmeron-Alcocer A, Rodriguez-Mendoza N, Pineda-Santiago S, Cristiani-Urbina E, Juarez-Ramirez C, Ruiz-Ordaz N, Galindez-Mayer J (2003) Aerobic treatment of maize processing wastewater (nejayote) in a single stream multi stage reactor. J Environ Eng Sci 2(5):401–406CrossRefGoogle Scholar
Pflugfelder RL, Rooney LW, Waniska RD (1988) Dry matter losses in commercial corn masa production. Cereal Chem 65:127–132Google Scholar
Jackson DS, Rooney LW, Kunze OR, Waniska RD (1988) Alkaline processing properties of stress cracked and broken corn (Zea mays L). Cereal Chem 65:133–137Google Scholar
Sahai D, Surjewan I, Mua JP, Buendia MO, Rowe M, Jackson DS (2000) Dry matter loss during nixtamalization of a white corn hybrid: Impact of processing parameters. Cereal Chem 77:254–258CrossRefGoogle Scholar
Gutiérrez-Uribe JA, Rojas-García C, García-Lara S, Serna-Saldivar SO (2010) Phytochemical analysis of wastewater (nejayote) obtained after lime-cooking of different types of maize kernels processed into masa for tortillas. J Cereal Sci 52:410–416CrossRefGoogle Scholar
Sahai D, Mua JP, Surjewan I, Buendia MO, Rowe M, Jackson DS (2001) Alkaline processing (nixtamalization) of white Mexican corn hybrids for tortilla production: Significance of corn physicochemical characteristics and process conditions. Cereal Chem 78:116–120CrossRefGoogle Scholar
Martínez-Bustos F, Martínez-Flores H, Sanmartín-Martínez E, Sánchez-Sinencio F, Chang Y, Barrera-Arellano D, Rios E (2001) Effect of the components of maize on the quality of masa and tortillas during the traditional nixtamalization process. J Sci Food Agric 81:1455–1462CrossRefGoogle Scholar
Flores-Farías R, Martínez-Bustos F, Salinas-Moreno Y, Chang YK, Hernández JG, Ríos E (2000) Physicochemical and rheological characteristics of commercial nixtamalized Mexican maize flours for tortillas. J Sci Food Agric 80:657–664CrossRefGoogle Scholar
Lopez-Martinez LX, Oliart-Ros RM, Valerio-Alfaro G, Lee C, Parkin KL, Garcia HS (2009) Antioxidant activity, phenolic compounds and anthocyanins content of eighteen strains of Mexican maize. LWT-Food Sci & Technol 42:1187–1192CrossRefGoogle Scholar
Figueroa-González I, Quijano G, Ramírez G, Cruz-Guerrero A (2011) Probiotics and prebiotics—Perspectives and challenges. J Sci Food Agric 91:1341–1348CrossRefGoogle Scholar
Del Pozo-Insfran D, Brenes CH, Serna-Saldivar SO, Talcott ST (2006) Polyphenolic and antioxidant content of white and blue corn (Zea mays L.) products. Food Res Int 39(6):696–703CrossRefGoogle Scholar
Lee CH, Garcia HS, Parkin KL (2010) Bioactivities of kernel extracts of 18 strains of maize (Zea mays). J Food Sci 75(8):C667–C672CrossRefGoogle Scholar
Prochaska HJ, Talalay P (1988) Regulatory mechanism of monofunctional and bifuctional anticarcinogenic enzyme inducers in murine liver. Cancer Res 48:4776–4782Google Scholar
Lopez-Martinez LX, Parkin KL, García HS (2011) Phase II-inducing, polyphenols content and antioxidant capacity of corn (Zea mays L.) from phenotypes of white, blue, red and purple colors processed into masa and tortillas. Plant Foods Hum Nutr 66:41–47CrossRefGoogle Scholar
Cortés GA, Salinas MY, San Martín-Martinez E, Martinez-Bustos F (2006) Stability of anthocyanins of blue maize (Zea mays L.) after nixtamalization of separated pericarp-germ tip cap and endosperm fractions. J Cereal Sci 43:57–62CrossRefGoogle Scholar
Serna-Saldivar SO, Gomez MH, Almeida-Dominguez HD, Islas-Rubio A, Rooney LW (1993) A method to evaluate the lime cooking properties of corn (Zea mays). Cereal Chem 70:762–764Google Scholar
Abdel-Aal ESM, Hucl P (1999) A rapid method for quantifying total anthocyanins in blue aleurone and purple pericarp wheats. Cereal Chem 76:350–354CrossRefGoogle Scholar
Mora-Rochin S, Gutiérrez-Uribe JA, Serna-Saldivar SO, Sánchez-Peña P, Reyes-Moreno C, Milán-Carrillo J (2010) Phenolic content and antioxidant activity of tortillas produced from pigmented maize processed by conventional nixtamalization or extrusion cooking. J Cereal Sci 52:410–416CrossRefGoogle Scholar
Sen A, Bergvinson D, Miller SS, Atkinson J, Fulcher RG, Arnason JT (1994) Distribution and microchemical detection of phenolic acids, flavonoids, and phenolic acid amides in maize kernels. J Agric Food Chem 42:1879–1883CrossRefGoogle Scholar
García-Lara S, Bergvinson DJ, Burt AJ, Ramputh AI, Díaz-Pontones DM, Arnason JT (2004) The role of pericarp cell wall components in maize weevil resistance. Crop Sci 44:1546–1552CrossRefGoogle Scholar
Serna Saldivar SO (2010) Cereal grains: properties, processing and nutritional attributes. CRC Press, Boca RatonGoogle Scholar