Powder Metallurgy and Metal Ceramics

, Volume 49, Issue 11–12, pp 619–629 | Cite as

Stability of iron-based powders with different phase compositions in biological media

Theory, Manufacturing Technology, and Properties of Powders and Fibers

The interaction of iron-based powders with different phase compositions with model biological media is examined in experiments in vitro. The powders are synthesized from iron oxalates over a range from 450 to 830°C in a carbon-containing atmosphere and from citrates at 390 and 450°C with prolonged holding in a protective hydrogen atmosphere. The phase composition of the powders is determined using a DRON 3.0 x-ray diffractometer in Co-K α radiation. Human blood plasma is used as a biological medium and distilled water and a 0.9% NaCl solution as inorganic media. It is shown that different processes occur in blood plasma and inorganic media: corrosion in water media and interaction between iron and proteins to form iron–protein complexes in plasma-containing media. The dissolution rate of the powders in blood plasma depends on their α-iron content: the higher the latter, the more active the interaction of the powder with plasma proteins such as ferritin and transferrin, basic components of γ-globulin fraction. The powders synthesized by the decomposition–reduction of citrates at 450 and 390°C with prolonged holding in a protective hydrogen atmosphere interact with model solutions of digestive juice far more intensely, which makes them promising for the development of iron-containing food supplements.


iron powders blood plasma digestive juice proteins 


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© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  1. 1.Frantsevich Institute for Problems of Materials ScienceNational Academy of Sciences of UkraineKievUkraine

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