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Plant Molecular Biology

, Volume 56, Issue 2, pp 217–224 | Cite as

Theatspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation

  • Jean-Yves Bleuyard
  • Maria E. Gallego
  • Charles I. White
Article

Abstract

Homologous recombination events occurring during meiotic prophase I ensure the proper segregation of homologous chromosomes at the first meiotic division. These events are initiated by programmed double-strand breaks produced by the Spo11 protein and repair of such breaks by homologous recombination requires a strand exchange activity provided by the Rad51 protein. We have recently reported that the absence of AtXrcc3, an ArabidopsisRad51 paralogue, leads to extensive chromosome fragmentation during meiosis, first visible in diplotene of meiotic prophase I. The present study clearly shows that this fragmentation results from un- or mis-repaired AtSpo11-1 induced double-strand breaks and is thus due to a specific defect in the meiotic recombination process.

Arabidopsis meiosis recombination Spo11 Xrcc3 

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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Jean-Yves Bleuyard
    • 1
  • Maria E. Gallego
    • 1
  • Charles I. White
    • 1
  1. 1.CNRS UMR6547Université Blaise PascalAubièreFrance

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