, Volume 16, Issue 2, pp 182–188 | Cite as

Sellar meningiomas: an endocrinologic perspective

  • Matheni Sathananthan
  • Airani Sathananthan
  • Bernd W. Scheithauer
  • Caterina Giannini
  • Fredric B. Meyer
  • John L. D. Atkinson
  • Dana Erickson


To review the clinical manifestations and outcomes of those with sellar meningiomas treated surgically at Mayo Clinic between 1975 and 2003. This is a retrospective chart and pathology review of 17 patients with a diagnosis of purely or largely intrasellar meningiomas treated surgically at our institution. Data in regards to presentation, endocrine hormonal status, surgical approach, pathology findings, outcome and adjunctive treatment were abstracted from the medical records. The majority of patients present with visual disturbances. All 17 tumors were WHO grade I. Surgical cure was achieved in 53 % after initial surgery. Postsurgical hypopituitarism occurred with high frequency. A substantial proportion of patients required subsequent surgical intervention or adjunctive treatment with external beam radiation. Sellar meningiomas are technically challenging and carry a high risk for visual disturbance and pituitary hormonal abnormalities. Many patients experience persistent disease requiring further intervention. These patients require long-term follow-up for evaluation of recurrence or development of new pituitary hormonal insufficiencies.


Sellar meningioma Intracranial tumor Pituitary insufficiency Visual disturbance 



We would like to dedicate this paper in memory of Dr. Bernd Scheithauer, who actively participated in preparation of this manuscript. We are grateful for his mentorship, collegiality, expertise, and his human spirit of generosity.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Matheni Sathananthan
    • 1
  • Airani Sathananthan
    • 2
  • Bernd W. Scheithauer
    • 3
  • Caterina Giannini
    • 3
  • Fredric B. Meyer
    • 4
  • John L. D. Atkinson
    • 4
  • Dana Erickson
    • 1
  1. 1.Department of EndocrinologyMetabolism and NutritionRochesterUSA
  2. 2.Division of Endocrinology, Diabetes and MetabolismWestern University of Health SciencesPomonaUSA
  3. 3.Laboratory Medicine and Anatomic PathologyMayo ClinicRochesterUSA
  4. 4.Neurological SurgeryMayo ClinicRochesterUSA

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