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Pituitary

, Volume 11, Issue 1, pp 85–87 | Cite as

An unusual association of a sellar gangliocytoma with a prolactinoma

  • Omar Serri
  • France Berthelet
  • Manon Bélair
  • Sophie Vallette
  • Sylvia L. Asa
Case Report

Abstract

The simultaneous occurrence of a hypothalamic and sellar gangliocytoma with a pituitary prolactinoma is very rare. The explanation for such an association is not known. We describe the case of a woman who had a coexisting adjacent pituitary prolactinoma and gangliocytoma within the same sellar mass. The tumor cells of the gangliocytoma demonstrated expression of enkephalin, a product of proopiomelanocortin known to be a prolactin secretagogue. We postulate that in this patient there may be a link between gangliocytoma enkephalin and prolactin hypersecretion.

Keywords

Prolactinoma Gangliocytoma Pituitary 

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Omar Serri
    • 1
  • France Berthelet
    • 1
  • Manon Bélair
    • 1
  • Sophie Vallette
    • 1
  • Sylvia L. Asa
    • 2
  1. 1.Departments of Medicine, Radiology and Pathology, CHUM Notre-Dame HospitalUniversity of MontrealMontrealCanada
  2. 2.University Health Network, University of TorontoTorontoCanada

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