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Phytochemistry and pharmacological activities of Vaccaria hispanica (Miller) Rauschert: a review

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Abstract

Vaccaria hispanica is utilized medicinally both in China and Turkey. Phytochemical screenings demonstrated that the phytochemical diversity of V. hispanica at least includes 63 distinct metabolites, embracing triterpenoid saponins, cyclic peptides, flavonoids and others. The pharmacological studies confirmed that the crude extracts or purified compounds from the plant showed galactopoietic activity, antitumor activity, effect on the blood and vessel, antioxidant activity, ameliorative effect on osteopenia and others. The present paper is aimed to provide a critical analysis of data from scientific evaluations and aimed to find out the linkage of the medicinal uses to the scientific studies. Simultaneously, the possible future direction and perspective for investigations are discussed, as well.

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Acknowledgments

We are grateful to Prof. Michael Heinrich, Prof. R. Verpoorte, Sarahann Kolder and reviewers, for their valuable comments and suggestions.

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  1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, No. 16 Nanxiaojie, Dongzhimennei Ave., Beijing, 100700, China

    Guohong Zhou, Liying Tang, Ting Wang, Xidan Zhou, Zhenzhen Kou & Zhuju Wang

  2. School of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Xitoutiao, Youanmenwai Ave., Beijing, 100069, China

    Jing Wu

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  1. Guohong Zhou
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  2. Liying Tang
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Correspondence to Zhuju Wang.

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Zhou, G., Tang, L., Wang, T. et al. Phytochemistry and pharmacological activities of Vaccaria hispanica (Miller) Rauschert: a review. Phytochem Rev 15, 813–827 (2016). https://doi.org/10.1007/s11101-015-9425-1

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