Abstract
Background Medication errors represent the most common type of error that compromises patient safety, with approximately 20% believed to result in harm. Over 40% of these errors are believed to result from inadequate medication reconciliation during admission, transfer, and discharge of patients and many of these errors could be prevented if adequate medication reconciliation processes were in place. In an effort to minimize adverse events caused during these care transitions, the Joint Commission has stated medication reconciliation as one of its National Patient Safety Goals and health care providers and organizations are encouraged to perform the process at various patient care transitions. Objective Identify the types of medication discrepancy that occurred during medication reconciliation performed by a pharmacist gathering the best possible medication history (BPMH). Estimate the potential for harm with each medication discrepancy using the severity rating methods developed by Cornish et al. (Arch Intern Med 165(4):424–429, 2005). Setting Tertiary care hospital in Jeddah, Saudi Arabia. Method Prospective 3-month study on 286 adult patients, admitted for at least 24 h and regularly taking at least four chronic prescription medications. Medication histories taken by physicians and by a pharmacist gathering the BPMH were compared. Identified discrepancies were reviewed by a panel of clinical pharmacists to assess the potential to cause patient harm with these errors. Main Outcome measure Number and types of medication discrepancies recorded by the pharmacist. Results Total number of medications recorded by physicians was 2548, versus 3085 by the pharmacist. 48.3% of patients had at least one unintended medication discrepancy by physicians. 537 medication discrepancies were reported (17.4% of number of medication discrepancies recorded by pharmacist). Types of medication discrepancies included, omissions (77% of discrepancies), commissions (13%), dosing errors (7%), and frequency errors (3%). 52% of the identified medication discrepancies had the potential to cause moderate to severe patient discomfort. Conclusion Patient medication histories are frequently recorded inaccurately by physicians during admission of patients which results in medication-related errors and compromises patient safety. Medication reconciliation is crucial in reducing these errors. Pharmacists can help in reducing these medication-related errors and the associated risks and complications.
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Abbreviations
- BPMH:
-
Best possible medication history
- MR:
-
Medication reconciliation
- PI:
-
Pharmacist investigator
- ISMP-Ca:
-
Institute for Safe Medication Practices Canada
References
https://www.ismp-canada.org/medrec/. Accessed 3 Oct 2016.
Reeder TA, Mutnick A. Pharmacist-versus physician-obtained medication histories. Am J Health Syst Pharm. 2008;65(9):857–60.
Beers MH, Munekata M, Storrie M. The accuracy of medication histories in the hospital medical records of elderly persons. J Am Geriatr Soc. 1990;38(11):1183–7.
The Joint Commission. Medication reconciliation. Sentinel event alert. 2006. http://www.jointcommission.org/SentinelEvents/SentinelEventAlert/sea_35.htm. Accessed 12 Nov 2016.
Rozich JD, Resar RK. Medication safety: one organization’s approach to the challenge. J Clin Outcomes Manag. 2001;8:27–34.
Vira T, Colquhoun M, Etchells E. Reconcilable differences: correcting medication errors at hospital admission and discharge. Qual Saf Health Care. 2006;15:122–6.
Gleason KM, Groszek JM, Sullivan C, Rooney D, Barnard C, Noskin GA, et al. Reconciliation of discrepancies in medication histories and admission orders of newly hospitalized patients. Am J Health Syst Pharm. 2004;16:1689–95.
Cornish PL, Knowles SR, Marchesano R, Tam V, Shadowitz S, Juurlink DN, et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005;165(4):424–9.
Crook M, Ajdukovic M, Angley C, Soulsby N, Doecke C, Stupans I, et al. Eliciting comprehensive medication histories in the emergency department: the role of the pharmacist. Pharm Pract. 2007;5:78–84.
Dobrzanski S, Hammond I, Khan G, Holdsworth H. The nature of hospital prescribing errors. Br J Clin Gov. 2002;7:187–93.
Abuyassin BH, Aljadhey H, Al-Sultan M, Al-Rashed S, Adam M, Bates DW, et al. Accuracy of the medication history at admission to hospital in Saudi Arabia. Saudi Pharm J. 2011;19(4):263–7.
Bond CA, Raehl CL, Franke T. Clinical pharmacy services, hospital pharmacy staffing, and medication errors in United States hospitals. Pharmacotherapy. 2002;22:134–47.
Lubowski TJ, Cronin LM, Pavelka RW, Briscoe-Dwyer LA, Briceland LL, Hamilton RA, et al. Effectiveness of a medication reconciliation project conducted by PharmD students. Am J Pharm Educ. 2007;71(5):94.
Karnon J, Campbell F, Czoski-Murray C. Model-based cost-effectiveness analysis of interventions aimed at preventing medication error at hospital admission (medicines reconciliation). J Eval Clin Pract. 2009;15:299–306.
Acknowledgements
The authors thank Oyindamola B Yusuf, Epidemiologist, at King Abdullah International Medical Research Center (yusufoy@ngha.med.sa) for her assistance with the statistical analysis of research data and Dr. Adel Ibrahem, MD, MDPH (adelmorsy3@gmail.com) for his help and support with statistical analysis.
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No external sources of funding were used for this study or for the writing, correction, and submission of this article.
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Abdulghani, K.H., Aseeri, M.A., Mahmoud, A. et al. The impact of pharmacist-led medication reconciliation during admission at tertiary care hospital. Int J Clin Pharm 40, 196–201 (2018). https://doi.org/10.1007/s11096-017-0568-6
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DOI: https://doi.org/10.1007/s11096-017-0568-6