International Journal of Clinical Pharmacy

, Volume 37, Issue 6, pp 975–977 | Cite as

NSAIDs in paediatrics: caution with varicella!

  • L. Durand
  • P. Sachs
  • C. Lemaitre
  • M. Lorrot
  • J. Bassehila
  • O. Bourdon
  • S. Prot-LabartheEmail author


Anti-inflammatory drugs have been suspected on several occasions to have promoted development of bacterial infection among varicella patients. Some countries have not implemented childhood varicella vaccination. Three cases in our hospital suggested the predisposing role of NSAIDs in varicella patient deterioration. Open access to these drugs widely increases their use and patient information should be continually provided in the medical offices and at dispensing pharmacy counters. Taking account of the benefit/risk balance and applying the simple precautionary principle, it would be appropriate to be cautious about the use of NSAIDs in the paediatric population.


Bacterial complications Children Ibuprofen Infection NSAIDs Paediatrics Varicella 




Conflicts of interest



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Copyright information

© Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie 2015

Authors and Affiliations

  • L. Durand
    • 1
    • 2
  • P. Sachs
    • 3
  • C. Lemaitre
    • 4
  • M. Lorrot
    • 4
  • J. Bassehila
    • 5
  • O. Bourdon
    • 1
    • 2
    • 6
  • S. Prot-Labarthe
    • 1
    • 2
    • 7
    Email author
  1. 1.PharmacieHôpital Robert-Debré, APHPParisFrance
  2. 2.Pharmacie CliniqueUniversité Paris Descartes, Sorbonne Paris CitéParisFrance
  3. 3.Réanimation pédiatriqueHôpital Robert-Debré, APHPParisFrance
  4. 4.Pédiatrie GénéraleHôpital Robert-Debré, APHPParisFrance
  5. 5.Service de Pharmacologie Pédiatrique et PharmacogénétiqueHôpital Robert-Debré, APHPParisFrance
  6. 6.Laboratoire Educations et Pratiques de Santé, EA 3412 Université Paris 13, Sorbonne Paris CitéBobignyFrance
  7. 7.INSERM, ECEVE U1123ParisFrance

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