Large discrepancies in linezolid use between French teaching hospitals: A comment on “Antimicrobial stewardship and linezolid”
Letter to the Editor
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We read with great interest in a recent issue of the International Journal of Clinical Pharmacy the article by Guillard et al. [ 1]. In this study, they stated that linezolid was used inappropriately in 40 % of cases in their hospital. We would like to discuss their results in light with a recent observational prospective study that we led in two large teaching hospitals: Nantes University Hospital (Hôtel-Dieu and Mother and Children’s sites) and Angers University Hospital, during a 6-month period in 2012. Each hospital included intensive care, dermatology, hematology, emergency, infectious disease (ID), pediatric, surgical and gynecology-obstetrics units, allowing comparison to Caen data. All prescriptions of linezolid were included. A data-collection card was created and completed using the patients’ medical files, prescriptions collected by the pharmacy and patients’ computerized files. Major results are shown in Table 1. Although linezolid use was mostly off-label in...
KeywordsVancomycin Linezolid Methicillin Antimicrobial Stewardship Microbiological Result
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