Abstract
Background Beyond the direct pharmacological effect of medicines, preferences and perceptions toward a particular oral solid dosage form (OSDF) play a crucial role in recovery and may reduce adherence to the prescribed treatment. Objectives This study conducted to investigate the most preferred OSDF and the degree to which swallowing solid medication is an issue, to assess perceptions of the therapeutic benefits of the OSDF, and to find predictors of the most preferred OSDF. Method A cross-sectional study, through convenience sample method, was conducted to survey consumers visiting community pharmacies in Baghdad, Iraq. Data was collected by selfadministered and pre-piloted questionnaires, and analyzed using Statistical Package for Social Science. Multiple logistic regression analysis and Chi-square tests were used at alpha level = 0.05. Results A total of 1,000 questionnaire were included in the analysis. Of all respondents, 52.9 % preferred capsule among other OSDF and this preference varied significantly with a number of socio-demographic factors. Ease of swallowing solid medication was the main issue which resulted in preferences for a particular form. A negative perception of the therapeutic benefits of the OSDF was found among 89.1 % of the consumers. Multiple logistic regression analysis indicated that gender, ease of swallowing, and perceptions of the therapeutic benefits of the OSDF were significant predictors of capsule preferences. Conclusions Given the fact that consumers are the end users of medicines and their preferences may influence response to the treatment, efforts are worthwhile by the prescribers and medicines’ manufactures to understand consumers’ preferences of a particular dosage form in order to achieve successful therapy outcomes.
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References
Buckalew L, Sallis R. Patient compliance and medication perception. J Clin Psychol. 1986;42:49–53.
Buckalew L, Ross S. Medication property effects on expectations of action. Drug Dev Res. 1991;23:101–8.
Reisenwitz T, Wimbish G. Over the counter pharmaceuticals: exploratory research of consumers preferences toward solid oral dosage forms. Health Mark Q. 1996;13:47–61.
Al-Shammari A, Khoja T, Al-Yamani J. Compliance with short-term antibiotic therapy among patients attending primary health centres in Riyadh, Saudi Arabia. J R Soc Health. 1995;115:231–4.
Hey H, Jorgenson F, Sorensen K, Wamberg T. Oesophageal transit of six commonly used tablet and capsules. Br Med J. 1982;285:1717–9.
Brotherman D, Bayraktaroglu T, Garofalo R. Comparison of ease of swallowing of dietary supplements products for age- related eye diseases. J Am Pharm Assoc. 2004;44:587–93.
Jones W, Francis J. Soft gels: consumers perceptions and market impact relative to other oral dosage forms. Adv Ther. 2000;17:213–21.
Brieger W, Salami K, Pshiname F. Perception of drug color among drug sellers and consumers in rural south western Nigeria. Res Social Adm Pharm. 2007;3:303–19.
Bhosle M, Benner J, DeKoven M, Shelton J. Difficult to swallow: patient preferences for alternative valproate pharmaceutical formulations. Patient Prefer Adherence. 2009;3:161–71.
Carnaby-Mann G, Crary M. Pill swallowing by adults with dysphagia. Arch Otolaryngology Head Neck Surg. 1970;131:970–5.
Overgaard A, Hojsted J, Hansen R. Moller- Sonnergaard J, Christrup L. Patients’ evaluation of shape, size, and color of solid dosage forms. Pharm World Sci. 2001;23:185–8.
Daher A, Amin F. Assessing the perceptions of a biostatistics and epidemiology module: view of year 2 medical students from a Malaysian university. A cross-sectional survey. BMC Med Educ. 2010;10:34.
Buckalew L, Coffield K. An investigation of drug expectancy as a function of capsule color and size and preparation form. J Clin Psychopharmacol. 1982;2:245–8.
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We would like to thank all the pharmacists who allowed the researchers to interview consumers at their own pharmacies in Baghdad. Further, we would like to thank all the participants for their time to complete the questionnaires.
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Ibrahim, I.R., Ibrahim, M.I.M. & Al-Haddad, M.S. The influence of consumers’ preferences and perceptions of oral solid dosage forms on their treatment. Int J Clin Pharm 34, 728–732 (2012). https://doi.org/10.1007/s11096-012-9667-6
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DOI: https://doi.org/10.1007/s11096-012-9667-6