Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia
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Case We report a case of simultaneous methemoglobinemia and hemolytic anemia, probably related to the use of rasburicase, in a child starting treatment for acute lymphoblastic leukemia (ALL). In addition, the patient developed symptoms of pancreatitis. All complications resolved after 3 days of supportive therapy. Conclusion Although usually well tolerated in pediatrics, physicians prescribing rasburicase should be aware of these possible life-threatening adverse reactions.
KeywordsClinical pharmacy Hemolytic anemia Methemoglobinemia Pancreatitis Pediatric hemato-oncology Rasburicase
Conflicts of interest
The authors have no conflicts of interest.
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