Pharmacotherapy update in the management of paediatric cancer
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Great advances in the treatment of childhood cancer have been made over the last 30 years because of developments in supportive care, the increasing use of advanced technology to detect and diagnose disease, developments in the understanding and relevance of cell biology and by the successful recruitment of children into nationally co-coordinated clinical trials. For some childhood malignancies where the survival rate is high, trials are ongoing to see if treatment can be stratified and directed according to patient risk, with those that fall into a favourable risk category potentially being cured with less treatment and therefore less short term and long term toxicity.
KeywordsPaediatric Cancer Pharmaceutical care Pharmacotherapy
Conflicts of interest
- 1.CRUK childhood cancer incidence. 2010. http://info.cancerresearchuk.org/cancerstats/childhoodcancer/incidence/index.htm. Accessed 27 June 2010.
- 2.CRUK childhood cancer treatment. 2010.http://info.cancerresearchuk.org/cancerstats/childhoodcancer/treatmentfollowup/index.htm. Accessed 27 June 2010.
- 3.CRUK childhood cancer trends. 2010. http://info.cancerresearchuk.org/cancerstats/childhoodcancer/trends/index.htm. Accessed 27 June 2010.
- 4.The rules governing medicinal products in the European Union Volume 10 clinical trials. 2010. http://ec.europa.eu/health/documents/eudralex/vol-10/index_en.htm. Accessed 27 June 2010.
- 5.Buckham J. How can we ensure child friendly oral chemotherapy agents are available? Pharm J. 2010;284:399–402.Google Scholar
- 8.NICE 2005. Improving outcomes for children and young people with cancer. http://www.nice.org.uk/nicemedia/live/10899/28876/28876.pdf. Accessed 27 June 2010.
- 9.DH National Cancer Action Team Manual for Cancer Services 2008: children’s cancer measures. http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_108670.pdf. Accessed 27 June 2010.