Study on the use of drugs in patients with enteral feeding tubes
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Objective To describe the use of drugs in patients using Enteral Feeding Tubes (EFT) at a University Hospital in southern Brazil. Method A total of 315 medical charts of patients that had used EFT were analyzed. Variables of interest were: days the tube was used, number and frequency of drugs administered by the tube, pharmaceutical dosage forms and the number of tube exchanges per patients. Results The mean of age of the patients was 59 years (SD = 21) and 59% were male. A mean number of drugs prescribed per patient with tube administration were five. Almost all patients (95%) used some drugs in solid pharmaceutical preparations, mostly tablets (72%). About 158 different drugs were prescribed; for 23% of these, the prescription of liquid dosage forms was possible. The chance of changing the enteral tube was greater for patients that used more than five drugs enterally (OR = 4.8, 95% CI 2.8–8.2) and that had more than 13 drug administrations per day (OR = 5.3, 95% CI 3.1–9.3). Conclusion This study provides evidence that patients using more drugs enterally have a greater chance of having their enteral tube exchanged. Furthermore, it suggests a lack of knowledge of the health team with regard to the appropriateness of pharmaceutical preparations for this administration.
KeywordsBrazil Drugs Enteral feeding tube Forms of administration Pharmaceutical preparations
The authors thank to persons that contribute with this study, and the Department of Pharmacy and Service Nurses at the Porto Alegre Clinical Hospital.
Research Incentive Fund of Hospital de Clínicas de Porto Alegre.
Conflict of interest
- 4.Thomson FC, Naysmith MR, Lindsay A. Managing drug therapy in patients receiving enteral and parenteral nutrition. Hosp Pharm. 2000;7:155–64.Google Scholar
- 6.Bauer LA. Interference of oral phenytoin absorption by continuous nasogastric feeding. Neurology. 1992;32:570–2.Google Scholar
- 8.Dickerson RN. Medication administration considerations for patients with enteral feeding tubes. Hosp Pharm. 2004;39:84–90.Google Scholar
- 9.Trissel LA. Trissel’s—stability of compounded formulations. 3rd ed. Washington: American Pharmaceutical Association; 2005. ISBN 978-1-58212-067-6.Google Scholar