A search for a modern method to determine the radiochemical purity of an 111In-oxine radiopharmaceutical composition resulted in the selection of a chromatography system that could perform quality control rapidly, consistently, and more accurately than an extraction method. The simplicity of the method made it accessible and convenient for performing quality control in medical institutions immediately before labeling leukocytes and stem cells.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 10, pp. 54 – 58, October, 2018.
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Taratonenkova, N.A., Lyamtseva, E.A., Malysheva, A.O. et al. Quality Control Method for 111In-Oxine Radiopharmaceutical Composition. Pharm Chem J 52, 868–872 (2019). https://doi.org/10.1007/s11094-019-1918-6
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DOI: https://doi.org/10.1007/s11094-019-1918-6