Validation of a Quantitative Determination Method for Ormustine in a Lyophilized Dosage Form

  • N. D. Bunyatyan
  • L. L. Nikolaeva
  • Yu. V. Olefir
  • E. V. Sanarova
  • N. A. Oborotova
  • A. B. Prokof’ev
  • E. V. Ignat’eva
  • I. V. Yartseva
  • I. D. Gulyakin
Article
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Validation results for a spectrophotometric quantitative determination method for ormustine in a lyophilized dosage form are presented. The method is shown to be suitable for quantitative determination of ormustine with respect to parameters such as specificity, linearity, accuracy, repeatability, and intermediate precision.

Keywords

validation spectrophotometry ormustine 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • N. D. Bunyatyan
    • 1
    • 2
  • L. L. Nikolaeva
    • 1
    • 3
  • Yu. V. Olefir
    • 2
  • E. V. Sanarova
    • 3
  • N. A. Oborotova
    • 1
    • 2
  • A. B. Prokof’ev
    • 1
    • 2
  • E. V. Ignat’eva
    • 3
  • I. V. Yartseva
    • 3
  • I. D. Gulyakin
    • 3
  1. 1.I. M. Sechenov First Moscow State Medical University (Sechenov University)MoscowRussia
  2. 2.Scientific Centre for Expert Evaluation of Medicinal ProductsMinistry of Health of the Russian FederationMoscowRussia
  3. 3.N. N. Blokhin Russian Oncological Research CenterRussian Academy of Medical SciencesMoscowRussia

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