Biologically Active Compounds in Aqueous Extracts of Caragana jubata (Pall.) Poir.

  • P. A. Kakorin
  • I. B. Perova
  • E. D. Rybakova
  • K. I. Éller
  • G. V. Ramenskaya
  • L. A. Pavlova
  • Yu. O. Teselkin
MEDICINAL PLANTS
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Polyphenolic compounds (flavonoids) of lyophilized aqueous extracts from Caragana jubata (Pall.) Poir. raw material from 2010 and 2015 were studied using modern HPLC-DAD-MS. Primarily mono- and diglycosides of O-hydroxylated (myricetin, quercetin, kaempferol) and O-methylated flavonols (isorhamnetin, laricitrin, syringetin) were identified. Long-term storage of dried raw material under standard conditions had little effect on the quantitative content of polyphenolic compounds. Acute toxicity studies of C. jubata extract showed no toxicity.

Keywords

Caragana jubata (Pall.) Poir. HPLC-DAD-MS flavonoids acute toxicity 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • P. A. Kakorin
    • 1
  • I. B. Perova
    • 1
    • 2
  • E. D. Rybakova
    • 1
  • K. I. Éller
    • 2
  • G. V. Ramenskaya
    • 1
  • L. A. Pavlova
    • 1
  • Yu. O. Teselkin
    • 3
  1. 1.I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)MoscowRussia
  2. 2.Federal Research Center of Nutrition and BiotechnologyMoscowRussia
  3. 3.N. I. Pirogov Russian National Research Medical UniversityMoscowRussia

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