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Biologically Active Compounds in Aqueous Extracts of Caragana jubata (Pall.) Poir.

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Polyphenolic compounds (flavonoids) of lyophilized aqueous extracts from Caragana jubata (Pall.) Poir. raw material from 2010 and 2015 were studied using modern HPLC-DAD-MS. Primarily mono- and diglycosides of O-hydroxylated (myricetin, quercetin, kaempferol) and O-methylated flavonols (isorhamnetin, laricitrin, syringetin) were identified. Long-term storage of dried raw material under standard conditions had little effect on the quantitative content of polyphenolic compounds. Acute toxicity studies of C. jubata extract showed no toxicity.

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Authors and Affiliations

  1. I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), 8 – 2 Malaya Trubetskaya St., Moscow, 119991, Russia

    P. A. Kakorin, I. B. Perova, E. D. Rybakova, G. V. Ramenskaya & L. A. Pavlova

  2. Federal Research Center of Nutrition and Biotechnology, 2/14 Ust’inskii Proezd, Moscow, 109240, Russia

    I. B. Perova & K. I. Éller

  3. N. I. Pirogov Russian National Research Medical University, 1/9 Ostrovityanova St., Moscow, 117997, Russia

    Yu. O. Teselkin

Authors
  1. P. A. Kakorin
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  2. I. B. Perova
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  3. E. D. Rybakova
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  4. K. I. Éller
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  5. G. V. Ramenskaya
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  6. L. A. Pavlova
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  7. Yu. O. Teselkin
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Corresponding author

Correspondence to P. A. Kakorin.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 11, pp. 29 – 34, November, 2017.

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Kakorin, P.A., Perova, I.B., Rybakova, E.D. et al. Biologically Active Compounds in Aqueous Extracts of Caragana jubata (Pall.) Poir.. Pharm Chem J 51, 1014–1020 (2018). https://doi.org/10.1007/s11094-018-1731-7

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  • DOI: https://doi.org/10.1007/s11094-018-1731-7

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