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Pharmaceutical Chemistry Journal

, Volume 50, Issue 10, pp 698–703 | Cite as

Pilot and Industrial Absorption-Chromatographic and Membrane Technologies for Isolation and Purification of Plant- and Animal-Based Active Pharmaceutical Ingredients

  • I. A. Narkevich
  • A. A. Semin
  • N. S. Kartashova
  • A. A. Teslev
EQUIPMENT FOR CHEMICO-PHARMACEUTICAL PLANTS MECHANIZATION AND AUTOMATION OF TECHNOLOGICAL PROCESSES
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Development and implementation of pilot and industrial absorption-chromatographic and membrane technologies for the isolation and purification of plant- and animal-based APIs are extremely important issues for the domestic pharmaceutical industry in the RF. The potential of using available Russian scientific and human resources for development and rapid implementation of competitive industrial production technologies with the lowest operating costs and greatest economic efficiencies is demonstrated.

Keywords

active pharmaceutical ingredient drugs plant- and animal-based raw materials local production scientific research and development implementation import replacement 

References

  1. 1.
    I. A. Narkevich, I. N. Tarasov, Z. M. Golant, et al., Khim.-farm. Zh., 49(11), 36 – 40 (2015); Pharm. Chem. J., 49(11), 760 – 764 (2016).Google Scholar
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    A. N. Serkova, Candidate Dissertation, St. Petersburg (2015).Google Scholar
  3. 3.
    Pall Chromatographic Products; http://www.gmpua.com/Validation/Filtration/03PallProcessChromatography.pdf, (accession date Jul. 20, 2015), free, in Russian.
  4. 4.
    State Contracts Under the Federal Targeted Program; http://fcp.economy.gov.ru/cgi-bin/cis/fcp.cgi/Fcp/ViewGkTable?fcp=350&csr=1008700&inv=2&year=2013 (accessiondate Jul. 20, 2015), free, in Russian.

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • I. A. Narkevich
    • 1
  • A. A. Semin
    • 2
  • N. S. Kartashova
    • 1
  • A. A. Teslev
    • 1
  1. 1.St. Petersburg State Chemico-Pharmaceutical AcademySt. PetersburgRussia
  2. 2.Ministry of Education and Science of the Russian FederationMoscowRussia

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