Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation
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Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required amben release kinetics.
Keywordshydrophobic polymer matrix amben prolonged release granulation
The work was supported financially by the RF Ministry of Education and Science (Contract No. 02.G25.31.0001) under the auspices of RF Administration Decree No. 218 of Apr. 9, 2010, and utilized equipment of the Center for Collective Use of Unique Scientific Equipment for MPTI nanotechnology studies.
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