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Pharmaceutical Chemistry Journal

, Volume 49, Issue 10, pp 711–714 | Cite as

Amperometric Detection Under Batch-Injection Analysis Conditions of Caffeine on an Electrode Modified by Mixed-Valence Iridium and Ruthenium Oxides

  • L. G. Shaidarova
  • I. A. Chelnokova
  • M. A. Degteva
  • G. F. Makhmutova
  • Yu. A. Leksina
  • A. V. Gedmina
  • G. K. Budnikov
STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL

Mixed-valence Ir–Ru oxides (IrOx—RuOx) electrodeposited on a glassy-carbon electrode surface were found to exhibit catalytic activity for caffeine oxidation. An amperometric method for caffeine detection at this modified electrode under batch-injection analysis conditions was developed. The analytical signal was linearly dependent on the caffeine concentration in the range 5 × 10−8 – 5 × 10−3 M. The developed method was tested for caffeine determination in tablets, solutions for injection of caffeine—sodium benzoate, and coffetamin tablets.

Keywords

chemically modified electrodes mixed-valence Ir–Ru oxides caffeine electrochemical oxidation batch-injection analysis 

Notes

Acknowledgments

The work was sponsored by the Russian Foundation for Basic Research (Grant No. 13-03-01101).

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • L. G. Shaidarova
    • 1
  • I. A. Chelnokova
    • 1
  • M. A. Degteva
    • 1
  • G. F. Makhmutova
    • 1
  • Yu. A. Leksina
    • 1
  • A. V. Gedmina
    • 1
  • G. K. Budnikov
    • 1
  1. 1.A. M. Butlerov Chemical InstituteKazan Federal UniversityKazanRussian Federation

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