Sterilizing Filtration for Production of Strontium-82 Active Pharmaceutical Ingredient
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Sterilizing filtration for the production of strontium-82 obtained after radiochemical processing of irradiated rubidium-metal targets was developed. Pharmacopoeial microbiology sterility tests established that the process produced sterile Sr-82 active pharmaceutical ingredient and could be recommended for producing 82Sr/82Rb generators.
Keywordsnuclear medicine strontium-82 sterilizing filtration active pharmaceutical ingredient 82Sr/82Rb generator
The work was sponsored by the Ministry of Education and Science of the Russian Federation on the topic “Development of manufacturing technology for strontium-82, raw material for producing radiopharmaceuticals” under State Contract No. 16.522.12.2012.
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