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Extraction of Sr-82, Raw Material for Radiopharmaceutical Production

  • Drug Synthesis Methods and Manufacturing Technology
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Pharmaceutical Chemistry Journal Aims and scope

A method for producing strontium-82, which is used in nuclear medicine for the preparation of rubidium-82 generators that are used in positron-emission tomography (PET) diagnostics of cardiovascular diseases, was described. The method consisted of irradiation of natural rubidium metal in a proton beam of energies from 40 to 100 MeV followed by radiochemical extraction of the produced strontium-82. The method enabled the irradiated target to be processed safely with simultaneous disposal of the rubidium metal and will be used for strontium-82 production at IPPE (Obninsk).

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Acknowledgments

The work was performed under the auspices of State Contract No. 16.522.12.2012 of the Ministry of Education and Science.

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Authors and Affiliations

  1. Leipunsky Institute for Physics and Power Engineering (IPPE), State Scientific Center of the Russian Federation, Obninsk, Kaluga Region, Russia

    A. V. Dunin, N. A. Nerozin, N. R. Togaeva, S. V. Khamyanov & V. V. Shapovalov

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  1. A. V. Dunin
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  2. N. A. Nerozin
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  3. N. R. Togaeva
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  4. S. V. Khamyanov
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  5. V. V. Shapovalov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 6, pp. 41 – 43, June, 2014.

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Dunin, A.V., Nerozin, N.A., Togaeva, N.R. et al. Extraction of Sr-82, Raw Material for Radiopharmaceutical Production. Pharm Chem J 48, 395–397 (2014). https://doi.org/10.1007/s11094-014-1118-3

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  • DOI: https://doi.org/10.1007/s11094-014-1118-3

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