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Pharmaceutical Chemistry Journal

, Volume 48, Issue 6, pp 395–397 | Cite as

Extraction of Sr-82, Raw Material for Radiopharmaceutical Production

  • A. V. Dunin
  • N. A. Nerozin
  • N. R. Togaeva
  • S. V. Khamyanov
  • V. V. Shapovalov
Drug Synthesis Methods and Manufacturing Technology

A method for producing strontium-82, which is used in nuclear medicine for the preparation of rubidium-82 generators that are used in positron-emission tomography (PET) diagnostics of cardiovascular diseases, was described. The method consisted of irradiation of natural rubidium metal in a proton beam of energies from 40 to 100 MeV followed by radiochemical extraction of the produced strontium-82. The method enabled the irradiated target to be processed safely with simultaneous disposal of the rubidium metal and will be used for strontium-82 production at IPPE (Obninsk).

Keywords

nuclear medicine strontium-82 rubidium-82 extraction chromatography ion exchange 

Notes

Acknowledgments

The work was performed under the auspices of State Contract No. 16.522.12.2012 of the Ministry of Education and Science.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • A. V. Dunin
    • 1
  • N. A. Nerozin
    • 1
  • N. R. Togaeva
    • 1
  • S. V. Khamyanov
    • 1
  • V. V. Shapovalov
    • 1
  1. 1.Leipunsky Institute for Physics and Power Engineering (IPPE), State Scientific Center of the Russian FederationObninskRussia

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