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Pharmaceutical Chemistry Journal

, Volume 47, Issue 10, pp 569–571 | Cite as

Quantitative Determination in Aqueous Solutions of Physiologically Active Copolymers of N-Vinylpyrrolidone and 2-Methyl-5-Vinylpyridine

  • S. A. Kedik
  • A. V. Panov
  • I. V. Sakaeva
  • Yu. V. Kochkina (Cherta)
  • D. V. Eremin
  • V. V. Suslov
  • M. A. Zaitsev
Article
  • 51 Downloads

Techniques for quantitative determination of N-vinylpyrrolidone and 2-methyl-5-vinylpyridine copolymers in aqueous solutions were developed. The spectrophotometric technique allowed the copolymer concentration in dilute solutions (0.8 – 1.2 mg/mL) to be determined even in the presence of the interfering additive merthiolate. The refractometric technique was simpler and allowed the copolymer concentration in concentrated solutions (> 1 mass%) to be determined.

Keywords

quantitative determination N-vinylpyrrolidone and 2-methyl-5-vinylpyridine copolymer aqueous solutions 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • S. A. Kedik
    • 1
  • A. V. Panov
    • 1
  • I. V. Sakaeva
    • 2
  • Yu. V. Kochkina (Cherta)
    • 1
  • D. V. Eremin
    • 1
  • V. V. Suslov
    • 1
  • M. A. Zaitsev
    • 3
  1. 1.Institute of Pharmaceutical TechnologiesMoscowRussia
  2. 2.State Scientific Center for Drug Expertise and Control, Ministry of the Russian Federation for Public HealthMoscowRussia
  3. 3.Space Research Institute, Russian Academy of SciencesMoscowRussia

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