Pharmaceutical Chemistry Journal

, Volume 47, Issue 10, pp 562–565 | Cite as

Alternative Road for Synthesis of 16α,17α-Epoxy-Pregn-4,9(11)-Dien-21-ol-3,20-Dione from 9α-Hydroxy-Androstenedione


An alternative efficient road for the synthesis of 16α,17α-epoxy-pregn-4,9(11)-dien-21-ol-3,20-dione from 9α-hydroxy-androst-4-ene-3,17-dione via its Δ9-analog has been studied.

Key words

Synthesis 16α,17α-epoxy-pregn-4,9(11)-diene-21-ol-3,20-dione 



One of the authors (L. D. H.) gratefully acknowledges support from the National Foundation for Science and Technology Development (grant no.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Institute of Chemistry, Vietnamese Academy of Science and TechnologyHa NoiVietnam

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