5-Aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones were synthesized using the reaction of ethanolamine with a mixture of aromatic aldehyde and methyl acylpyruvates. The antibacterial activity of the synthesized compounds was studied.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2010), pp. 116, 214, 556, 616, 788.
J. Coleman and K.-G. Rem, Descriptive Biochemistry [Russian translation], Mir, Moscow (2000), p. 409.
V. L. Gein, A. A. Bobyleva, E. B. Levandovskaya, et al., Khim.-farm. Zh., 1(46), 26 – 28 (2012).
V. L. Gein, Tetrahydropyrrole- and Tetrahydrofuran-2,3-diones [in Russian], PSPA, Perm (2004), p. 84.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 10, pp. 30 – 32, October, 2013.
Rights and permissions
About this article
Cite this article
Gein, V.L., Odegova, T.F., Korol’, A.N. et al. Synthesis and antibacterial activity of 5-aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones. Pharm Chem J 47, 536–538 (2014). https://doi.org/10.1007/s11094-014-0999-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-014-0999-5