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Pharmaceutical Chemistry Journal

, Volume 46, Issue 4, pp 225–227 | Cite as

Chemical constituents of Ficus odorata

  • P.-W. Tsai
  • K. A. De Castro-Cruz
  • C.-C. Shen
  • C.-T. Chiou
  • C. Y. Ragasa
Article

A dichloromethane extract of the leaves of Ficus odorata (Moreaceae family) contains l-sitosteryl3β-glucopyranoside-6'-O-palmitate (1), squalene (2), lutein (3), α-amyrin acetate (4), lupeol acetate (5), and β-carotene (6). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 was tested for cytotoxicity using sulforhodamine B assay against the human lung adenocarcinoma epithelial cell line (A549), human stomach adenocarcinoma cell line (AGS), human colon adenocarcinoma (HT29) and human prostate cancer cell line (PC3). It exhibited cytotoxicity against AGS cell line with 60.28% growth inhibition

Key words

Ficus odorata Moreaceae β-sitosteryl-3β-glucopyranoside-6'-O-palmitate cytotoxicity 

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Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  • P.-W. Tsai
    • 1
  • K. A. De Castro-Cruz
    • 1
  • C.-C. Shen
    • 2
  • C.-T. Chiou
    • 2
  • C. Y. Ragasa
    • 3
    • 4
  1. 1.School of Chemical Engineering and ChemistryMapúa Institute of TechnologyManilaPhilippines
  2. 2.National Research Institute of Chinese MedicineTaipeiTaiwan
  3. 3.Chemistry Department, De La Salle UniversityManilaPhilippines
  4. 4.Center for Natural Sciences and Ecological ResearchDe La Salle UniversityManilaPhilippines

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