Succinic acid bas been found to be able to potentiate the antihypoxic activity of vinpocetin. This property (potentiation) provided grounds for creating a new combined formulation containing vinpocetin and succinic acid, which has more marked antihypoxic activity than the initial single-substance vinpocetin formulation, along with antiamnestic and anticonvulsive activities.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 4, pp. 9 – 11, April, 2011.
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Glushkov, R.G., Yuzhakov, S.D., Andreeva, N.I. et al. A potential combined formulation containing vinpocetin and succinic acid. Pharm Chem J 45, 205–207 (2011). https://doi.org/10.1007/s11094-011-0594-y
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DOI: https://doi.org/10.1007/s11094-011-0594-y